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transport systems"],"description":"Expected Outcome:Metro lines are traditionally operated through a combination of planned levels of demand and of availability of rolling stock and drivers along different periods of typical days. The adaptation of operations to face changes of the traffic patterns and levels are largely influenced by the constraints of staff management and by the knowledge of customers expectations.\nAdditionally, AI and data science are frequently praised as a solution to address transport issues by handling large set of data, combining information from many sources being indicators and sensors.\nThe Project stemming from this topic should aim to identify and initially exploit key areas of innovation of the future metro system. The initiative shall identify new requirements, develop new concepts, and implement early stages of development of the solutions based on new emerging technologies (automation and digitalization, AI, telecom, etc.).\nThese new technologies, concepts and new ways of operation shall contribute to a better mass rapid transport system with:\n• Optimized Capacity – Flexi Demand, making the most of the existing infra and rolling stock following customer commuting habits, flows and better managing disruptions.\n• Efficient Train Control Systems that enable cost reductions and better operational response.\n• Sustainable transport system, applying different technologies and concepts to better manage the total cost of ownership and deliver better energy footprint.\nThe final objective is to increase efficiency, sustainability, attractiveness, and resilience against current state of the art. Making the system future metro systems answering the needs of an evolving society with the metro as the backbone of urban mobility.\nScope:Considering the current state of the art regarding automation in the metro system, the action to be funded under this topic shall deliver R&I which first step is to determine requirements and needs for future different type of metro users, while also taking into consideration the resilience to external challenges/future threats (climate threats, sanitary, terrorism, etc.) aiming at making metro systems future proof.\nThe following R&I areas have been identified as key enablers of the expected outcome. The Project stemming from this topic shall address all the following work streams and is expected to provide all the following:\nWorkstream 1: Increased adaptability of metros to fluctuations in demand. The project shall deliver a feasibility study, potentially using simulation tools as Proof of Concept to demonstrate to what extent it is possible to increase the adaptability of metros to fluctuations in demand; and how to benefit from new opportunities provided by the trend towards full automation of metro operation (Grade of Operation 4 with no staff on board train), by a better knowledge of customers profiles and travel conditions (expected and actual) thanks to digitalization, by new technologies and by improved coordination with other modes and new mobility services.\nWorkstream 2: Future of train control. The project shall deliver a feasibility study, including an analysis of the different trends in train control and existing / future technological solutions as well as adefinition of future needs and functional requirements for the different categories of metro systems. The objective is not to focus on one solution with respect to another, but to explore equidistantly the topic from the different point of view like economic, operational, technologic and considering the potential impact on existing systems.\nWorkstream 3: Advantages and trends brought by AI and data science in metro operation for different types of metros (old/new, large/small, etc.). While their area of relevance is rather associated with large networks, the project shall deliver concepts on the most promising AI and data science implementation applications in metro operation, with a cost-effective approach, in different categories of metro systems (greenfield/brownfield, city or regional, connection with long distance modes...). Relevant aspects like application to operational processes and cybersecurity threat identification and management should also be considered. Preliminary results of this workstream may be considered for Workstream 1 and 2 implementations.\nInteractions with other EU-RAIL projects and EU-Missions\nThe action to be funded under this topic shall:\n• Take into account the outputs of linked projects from EU-RAIL Flagship Areas 1[1], 2[2] and 3[3] and work together with them for any potential interfaces.\n• Interact with EU-Rail System Pillar[4] for the aspects related to the interface between mainline rail (SERA) and urban mobility systems of which metro is part.\n• Explore possible collaboration with cities participating in the EU Mission for Climate-Neutral and Smart Cities[5].\nGender dimension\nIn this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement.\n[1] https://projects.rail-research.europa.eu/eurail-fp1/\n[2] https://projects.rail-research.europa.eu/eurail-fp2/\n[3] https://projects.rail-research.europa.eu/eurail-fp3/\n[4] https://rail-research.europa.eu/system_pillar/\n[5] https://ec.europa.eu/mission-cities and Cities Mission Platform https://netzerocities.eu","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-ER-JU-2023-EXPLR-02"}]}}
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feedback of research results into teaching and education at participating organisations.\nScope:Fellowships will be provided to excellent researchers undertaking international mobility. Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.\nPostdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:\n• European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.\n• Global Postdoctoral Fellowships are open to European nationals or long-term residents[1] who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. 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The secondment phase can be a single period or be divided into shorter mobility periods.\nFor European Postdoctoral Fellowships, secondments cannot exceed one third of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.\nFor Global Postdoctoral Fellowships, optional secondments are permitted for up to one third of the outgoing phase. A maximum of three months of such secondments can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.\nSecondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.\nPlacements in the non-academic sector\nPostdoctoral Fellowships can provide an additional period of up to six months to support researchers opting for a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country[3]. While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country[4]. The request for such a non-academic placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.\nIf the placement does not meet the requirements (taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. 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To that end, proposals under this topic should aim for delivering results that are directed, tailored towards and contributing to two of the three expected outcomes listed below:\n• Enrichment of the current portfolio of SARS-CoV-2 /COVID-19 prophylactics and therapeutics with clinical testing of promising candidates.\n• Further development of new, or adjustment of existing, vaccine candidates to be effective against the current SARS-CoV-2 variants and potentially protect against new emerging ones.\n• Development of new effective therapies against SARS-CoV-2 for the clinical management of COVID-19 disease, including for the prevention of disease progression to severe illness and hospitalisation.\nScope:\nProposals submitted under this expression of interest should aim to further develop promising therapeutic or prophylactic candidates against SARS-CoV-2/COVID-19. The vaccine/treatment candidates should have completed preclinical development, including animal studies, and be ready to enter clinical evaluation in Phase I or II studies. Applicants should have addressed the current viral variants of concern in their pre-clinical work, and/or anticipated the emergence of new variants. Proposals should include a summary of results obtained in the concluded studies (pre-clinical and/or Phase I). Proposals are also expected to include assurances on sufficient and timely access to GMP production of the compound(s) to be trialled (the costs of which can be included in the proposal). In addition, options to upscale production for subsequent development beyond the activities for which funding is requested, should be indicated as appropriate.\nThe proposed interventions should address, and be assessed for, different age population groups, including children and pregnant women, and target specific groups of interest such as immunocompromised, patients with co-morbidities or other groups with higher risk to develop severe disease, and patients suffering from long-term health consequences of COVID-19.\nThe therapeutic interventions to be developed should aim at treating mild to moderate illness (e.g. antivirals, antibodies, immunomodulators). Therapeutic interventions targeting severe to critical illness resulting from the infection are excluded.\nThermostability, innovative delivery systems, affordability and the flexibility of the platforms to speedily adjust the candidates to emerging variants, should be also considered when possible.\nSuccessful applicants are expected to engage early on with the European Medicines Agency (EMA) to ensure adequacy of the actions from a regulatory point of view.\nCollaboration with one of the large European trial networks VACCELERATE, RECOVER or EU-RESPONSE projects is expected and applicants are encouraged to describe their plans for such collaboration in the proposal[1].\nProposals should envisage an appropriate level of collaboration with existing European research infrastructures, and should link to the COVID-19 data portal[2] for the timely sharing of relevant data.\nGender-related issues are an important crosscutting priority of this Expression of Interest. All data should be sex- and gender-disaggregated, and attention should be paid to critical social factors intersecting with sex/gender, such as age, social origin, ethnicity/migration, and disability.\nThis action seeks to address the challenges linked to the COVID-19 variants. As such, the granting authority has activated the public emergency provisions included in the General Annexes, meaning that beneficiaries must comply with the public emergency related provisions listed in the General Annexes of the Work Programme 2021 (part G - Legal and financial set-up of the grant agreements) and in the Model Grant Agreement concerning the project implementation under Intellectual Property Rights (IPR), background and results, access rights and rights of use (article 16 and Annex 5) for the duration of the pandemic; and under Communication, dissemination, open science and visibility (article 17 and Annex 5) during the entire duration of the action and for four years after the end of the action.\nIt is expected that quality-controlled data are shared in accordance with the FAIR[3] principles. 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Systems","callIdentifier":"H2020-ICT-2014","callTitle":"ICT 2014 - Information and Communications Technologies","programme":"Horizon 2020 Framework Programme","programmeDivisions":["EC Treaty","Industrial Leadership","Information and Communication Technologies","A new generation of components and systems: Engineering of advanced embedded and energy and resource efficient components and systems","Leadership in enabling and industrial technologies (LEIT)"],"typeOfAction":"RIA Research and Innovation action","typeOfMGA":[],"status":"Closed","openingDate":null,"deadlineDates":[null],"budget":{"budgetByYear":{"0":649500000},"expectedGrants":null,"minContribution":null,"maxContribution":null,"deadlineModel":"single-stage"},"keywords":["Automation","Cyber-physical systems","Control engineering","Semiconductors","Electrical and electronic engineering: semiconduct","Systems engineering","Systems engineering, sensorics, actorics, automati"],"description":"Scope:Specific Challenge: Cyber-Physical Systems (CPS) refer to next generation embedded ICT systems that are interconnected and collaborating including through the Internet of things, and providing citizens and businesses with a wide range of innovative applications and services. These are the ICT systems increasingly embedded in all types of artefacts making \"smarter\", more intelligent, more energy-efficient and more comfortable our transport systems, cars, factories, hospitals, offices, homes, cities and personal devices. Focus is on both reinforcing European industrial strengths as well as exploring new markets.\nOften endowed with control, monitoring and data gathering functions, CPS need to comply with essential requirements like safety, privacy, security and near-zero power consumption as well as size, usability and adaptability constraints. To maximise impact and return on investment in this field, the following challenges must be addressed:\nDe-verticalising technology solutions with CPS platforms that cut across the barriers between application sectors including mass consumer markets.\nBringing together actors along the value chain from suppliers of components and customised computing systems to system integrators and end users.\nCreating new ICT Platforms for both vertical and core markets from automotive, health , smart buildings and energy to wireless communications and digital consumer products and services.\nScope: Activities should address the development of new paradigms, concepts, and platforms or toolboxes laying the foundation for future generations of CPS. Participants should include suppliers and users of CPS, tool providers, suppliers of sub-systems, system integrators, auditors/certification bodies of systems and related academia and research institutes (including Social Sciences and Humanities).\na.      Research & Innovation Actions should cover one or both of the following themes:\nModelling and integration frameworks: modelling techniques and comprehensive integrated tool chains for clearly defined use cases. Major aspects to be addressed include the holistic modelling of the system behavioural, computational, physical and/or human aspects of CPS; and the seamless interoperability between CPS tools. Solutions should ensure flexibility and tractability of systems.\nSmart, cooperative and open CPS: Methods for engineering Cyber-physical Systems that are able to respond in real-time to dynamic and complex situations while preserving control, system safety, privacy, reliability, energy efficiency and dependability features, and addressing security and privacy \"by design\" across all levels. This includes CPS that are aware of the physical environment, enabling effective and fast feedback loops between actuation and sensing, possibly with cognitive and learning capabilities; further CPS with cooperation and negotiation capabilities supporting distributed services, autonomous, reactive and targeted problem solving and/or improved man-machine interaction. Also covered are open and heterogeneous CPS and Systems of Systems to facilitate seamless connectivity, dynamic reconfiguration as well as handling of emergent properties. The developed methods should enable evolutionary, adaptive and iterative system life-cycles and guarantee Quality of Service at functional and extra-functional level.\nProjects are expected to be driven by industrial requirements, to be well balanced between industry and academia, and to include a demonstration and validation phase with realistic use cases.\nb.      Innovation Actions will stimulate innovation and connect innovators across value chains in view of broader adoption of novel embedded and cyber-physical systems technologies and their enablers in industrial and societal applications. Proposals should cover one or both of the following themes.\nTowards platforms and ecosystems: Prepare reference architectures and platforms for open, smart and co-operative CPS applicable across sectors and application domains, including industrial consensus building, reference implementations, pre-normative activities, proof-of concept demonstration, user involvement and validation in key application domains. Proposals requesting a Small contribution are expected.\nTowards a \"smart everywhere\" society: Support will go to the establishment of European networks of embedded systems design centres. The networks' goal will be to help businesses from any sector uplift the quality and performance of their products and services with innovative embedded ICT components and systems. This will be done through a number of development and experimenting actions conducted with the help of the centres. Clustered in large scale projects and driven by user requirements, these experiments must facilitate users-suppliers partnerships across value chains and regions. With special emphasis on SMEs and mid-caps, focus is on technologies and processes, which are customised, integrated, tested and validated at the system level. The network must include vertical competences from embedded software and systems down to the components subsystems and components level and foster collaboration and trust, as well as openness and pre-normative measures. Work should build on and be complementary to EU, national and regional activities such as pilot projects in ENIAC, ARTEMIS and ECSEL.\nProposals requesting a Large contribution are expected. The action may involve financial support to third parties in line with the conditions set out in Part K of the General Annexes. The consortium will define the selection process of additional users and suppliers running the experiments for which financial support will be granted (typically in the order of EUR 50.000 – 150.000 per party).  Maximum 50% of the EU funding requested by the proposal should be allocated to this purpose.\nc.       Support Actions for cross-sectorial platform-building, structuring of constituencies and road-mapping, dissemination of programme a","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/ICT-01-2014"}]}}
{"id":"101204286","acronym":"MP Valley Transistor","name":"Magneto Plasmonic Assisted Room Temperature Valleytronic Transistor","offer":"Modern information processing faces significant challenges, including high power consumption, speed saturation, and scaling limitations. Valleytronic transistors, exploiting the valley degree of freedom, offer energy-efficient operations by minimizing heat generation and increasing data densities. However, robust room-temperature valleytronic transistors are challenging due to strong intervalley scattering. This research aims to develop a groundbreaking magneto-plasmonic assisted room-temperature valleytronic transistor. The objective is to enhance the performance of room-temperature valley transistors through an innovative approach. The proposed method involves the combination of chiral plasmonic nanostructures with a ferromagnetic Fe3GaTe2 monolayer. The chiral plasmonic nanostructures are designed to selectively generate valley-polarized hot carriers in WS2, with their effectiveness further amplified by the magnetic proximity effect induced by Fe3GaTe2. This device can generate, propagate, detect, and manipulate valley information at room temperature, advancing energy-efficient electronic devices. This project could potentially mark a new milestone in the field of valleytronics. Warsaw University, with its state-of-the-art facilities and the expertise of Prof. Maciej Molas, provides the necessary resources and environment for the successful execution of this ambitious project. This research could revolutionize information processing and advance energy-efficient electronics. This research aligns closely with the objectives of the Work Programme by addressing the need for advancing energy-efficient electronic devices. This project aims to enhance sustainable and efficient information processing technologies by exploring valleytronic transistors and incorporating magneto-plasmonic assistance. Additionally, it will host Marie Curie fellows to promote international collaboration and knowledge exchange.","objective":"Modern information processing faces significant challenges, including high power consumption, speed saturation, and scaling limitations. Valleytronic transistors, exploiting the valley degree of freedom, offer energy-efficient operations by minimizing heat generation and increasing data densities. However, robust room-temperature valleytronic transistors are challenging due to strong intervalley scattering. This research aims to develop a groundbreaking magneto-plasmonic assisted room-temperature valleytronic transistor. The objective is to enhance the performance of room-temperature valley transistors through an innovative approach. The proposed method involves the combination of chiral plasmonic nanostructures with a ferromagnetic Fe3GaTe2 monolayer. The chiral plasmonic nanostructures are designed to selectively generate valley-polarized hot carriers in WS2, with their effectiveness further amplified by the magnetic proximity effect induced by Fe3GaTe2. This device can generate, propagate, detect, and manipulate valley information at room temperature, advancing energy-efficient electronic devices. This project could potentially mark a new milestone in the field of valleytronics. Warsaw University, with its state-of-the-art facilities and the expertise of Prof. Maciej Molas, provides the necessary resources and environment for the successful execution of this ambitious project. This research could revolutionize information processing and advance energy-efficient electronics. 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Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.\nPostdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:\n• European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.\n• Global Postdoctoral Fellowships are open to European nationals or long-term residents[1] who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. These fellowships require an outgoing phase of minimum 12 and maximum 24 months in a non-associated Third Country, and a mandatory 12-month return phase to a host organisation based in an EU Member State or a Horizon Europe Associated Country.\nSpecific eligibility conditions apply to MSCA Postdoctoral Fellowships in the research areas covered by the Euratom Research and Training Programme 2021-2025[1].\nSecondments\nResearchers receiving a Postdoctoral Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.\nFor European Postdoctoral Fellowships, secondments cannot exceed one third of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.\nFor Global Postdoctoral Fellowships, optional secondments are permitted for up to one third of the outgoing phase. A maximum of three months of such secondments can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.\nSecondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.\nPlacements in the non-academic sector\nPostdoctoral Fellowships can provide an additional period of up to six months to support researchers opting for a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country[3]. While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country[4]. The request for such a non-academic placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.\nIf the placement does not meet the requirements (taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. This might affect the final score.\nTraining activities\nThe training activities implemented under the Postdoctoral Fellowships should include training for key transferable skills, foster innovation and entrepreneurship, (e.g. commercialisation of results, Intellectual Property Rights, communication, public engagement and citizen science), foster good scientific conduct such as research integrity and promote Open Science practices (open access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science etc.).\nCareer Development Plan\nIn order to equip MSCA postdoctoral fellows with skills that enhance and expand their career opportunities inside and outside academia, a Career Development Plan should be established jointly by the supervisor(s) and the researcher. 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{"id":"101107964","acronym":"BACH","name":"The molecular suite of shell Bio- & ArCHaeochromes","offer":"Molluscs adorn their shells with an incredible diversity of colours and patterns which were highly appreciated since ancient times. Shell biochromes encode important biological information - they may play a role in immunity, shell strengthening, protection from thermal stress and UV radiation. They are also extremely durable in time – pigments can be found in fossil shells dating to millions of years.  Could shell biochromes be among the most promising ancient biomolecules? Despite the great diversity and complexity of shell colours, there is no complete molecular understanding of shell pigmentation in any mollusc system. The studies are limited and our knowledge how biochromes are mineralised (not to mention how they preserve) remains patchy. BAch will carry out an in-depth study of mollusc shell biochromes. The work will focus on a model species Littorina fabalis which displays colour polymorphism and are abundantly found in archaeological record, since they were used in prehistory. I will employ cutting-edge ‘ShellOmic’ techniques - transcriptomics and proteomics, coupled with the first application of CRISPR-Cas9 gene editing tool to elucidate the chemical nature of shell biochromes and associated proteins. Gene editing will help to verify genes that are involved in shell coloration and biomineralisation. The research and training will provide me with a novel set of skills reinforcing my position as an expert shell research. Finally, I will use palaeoproteomics, the analysis of ancient proteins by mass spectrometry techniques, to investigate the preservation potential of ancient biochromes, i.e. archaeochromes. In the future, we could use these as biomolecular colour markers to answer archaeological questions. BAch will address decades long query – what are the shell pigments and what biological information do they encode? My unique expertise, multidisciplinary network, international background and expert team on board will guide me to answer these questions.","objective":"Molluscs adorn their shells with an incredible diversity of colours and patterns which were highly appreciated since ancient times. Shell biochromes encode important biological information - they may play a role in immunity, shell strengthening, protection from thermal stress and UV radiation. They are also extremely durable in time – pigments can be found in fossil shells dating to millions of years.  Could shell biochromes be among the most promising ancient biomolecules? Despite the great diversity and complexity of shell colours, there is no complete molecular understanding of shell pigmentation in any mollusc system. 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Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.\nPostdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:\n• European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.\n• Global Postdoctoral Fellowships are open to European nationals or long-term residents[1] who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. These fellowships require an outgoing phase of minimum 12 and maximum 24 months in a non-associated Third Country, and a mandatory 12-month return phase to a host organisation based in an EU Member State or a Horizon Europe Associated Country.\nSpecific eligibility conditions apply to MSCA Postdoctoral Fellowships in the research areas covered by the Euratom Research and Training Programme 2021-2025[1].\nSecondments\nResearchers receiving a Postdoctoral Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.\nFor European Postdoctoral Fellowships, secondments cannot exceed one third of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.\nFor Global Postdoctoral Fellowships, optional secondments are permitted for up to one third of the outgoing phase. A maximum of three months of such secondments can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.\nSecondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.\nPlacements in the non-academic sector\nPostdoctoral Fellowships can provide an additional period of up to six months to support researchers opting for a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country[3]. While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country[4]. The request for such a non-academic placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.\nIf the placement does not meet the requirements (taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. This might affect the final score.\nTraining activities\nThe training activities implemented under the Postdoctoral Fellowships should include training for key transferable skills, foster innovation and entrepreneurship, (e.g. commercialisation of results, Intellectual Property Rights, communication, public engagement and citizen science), foster good scientific conduct such as research integrity and promote Open Science practices (open access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science etc.).\nCareer Development Plan\nIn order to equip MSCA postdoctoral fellows with skills that enhance and expand their career opportunities inside and outside academia, a Career Development Plan should be established jointly by the supervisor(s) and the researcher. In addition to research objectives, this plan should comprise the researcher's training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences and events aiming at opening science and research to citizens. The Plan will have to be submitted as a project deliverable at the beginning","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-MSCA-2024-PF-01-01"}]}}
{"id":"677898","acronym":"MARCAN","name":"Topographically-driven meteoric groundwater – An important geomorphic agent","offer":"Topographically-driven meteoric (TDM) recharge is a key driver of offshore groundwater systems because sea level has been lower than at present for 80% of the last 2.6 million years. Groundwater has been implicated as an important agent in the geomorphic evolution of passive continental margins and the canyons that incise them. However, the geomorphic efficacy of groundwater remains dubious, and a diagnostic link between landscape form and groundwater processes remains poorly quantified, especially for bedrock and cohesive sediments. Obstacles that prevent going beyond the current state-of-knowledge include: (i) a focus on terrestrial contexts and a lack of mechanistic understanding of groundwater erosion/weathering; (ii) limited information on offshore groundwater architecture, history and dynamics. By addressing the role of TDM offshore groundwater in the geomorphic evolution of the most prevalent types of continental margins, MARCAN is expected to open new scientific horizons in continental margin research and bring about a step-change in our understanding of some of the most widespread and significant landforms on Earth. The project’s methodology is rooted in an innovative, multi-scale and multidisciplinary approach that incorporates: (i) the most detailed 3D characterisation of TDM offshore groundwater systems and their evolution during an integral glacial cycle, based on state-of-the-art marine data and hydrogeologic models, and (ii) the development of a comprehensive continental margin geomorphic evolution model, based on realistic laboratory simulations, accurate field measurements and advanced numerical solutions. By placing better constraints on past fluid migration histories, MARCAN will also have strong applied relevance, primarily by improving assessment and exploitation of offshore freshwater as a source of drinking water.","objective":"Topographically-driven meteoric (TDM) recharge is a key driver of offshore groundwater systems because sea level has been lower than at present for 80% of the last 2.6 million years. Groundwater has been implicated as an important agent in the geomorphic evolution of passive continental margins and the canyons that incise them. However, the geomorphic efficacy of groundwater remains dubious, and a diagnostic link between landscape form and groundwater processes remains poorly quantified, especially for bedrock and cohesive sediments. Obstacles that prevent going beyond the current state-of-knowledge include: (i) a focus on terrestrial contexts and a lack of mechanistic understanding of groundwater erosion/weathering; (ii) limited information on offshore groundwater architecture, history and dynamics. By addressing the role of TDM offshore groundwater in the geomorphic evolution of the most prevalent types of continental margins, MARCAN is expected to open new scientific horizons in continental margin research and bring about a step-change in our understanding of some of the most widespread and significant landforms on Earth. The project’s methodology is rooted in an innovative, multi-scale and multidisciplinary approach that incorporates: (i) the most detailed 3D characterisation of TDM offshore groundwater systems and their evolution during an integral glacial cycle, based on state-of-the-art marine data and hydrogeologic models, and (ii) the development of a comprehensive continental margin geomorphic evolution model, based on realistic laboratory simulations, accurate field measurements and advanced numerical solutions. 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The applicants are encouraged to consider a project duration of up to 12 months and in their proposals they should:\n• Identify areas and activities of cooperation to enhance the coordination and directionality of their research and innovation investments and policies and improve the efficiency and performance of the EU's innovation ecosystems, fostering their interconnection and scale-up while tackling EU, national, regional and/or local challenges:   • The proposals may focus on a thematic/technological area of common interest in line with one or more EU priorities, including climate action, Green Deal and digital transformation, including those specified in the New European Innovation Agenda;\n• The proposals should pay attention to gender equality objectives[5].\n• Plan their long-term commitment: the applicants are encouraged to consider planning commitments of at least three (3) years towards engaging in the joint cooperation activities set out in the frame of the projects;\n• Explain the potential for growth and competitiveness foreseen in the targeted sector and/or expected impact on relevant EU challenges through the proposed cooperation;\n• Ensure inclusiveness and diversity with the involvement of all innovation actors, including individual inventors, enhance complementarities of EU, national and/or regional funds and programmes, and encourage the alignment of their innovation agendas;\n• Provide a justification on the need for those joint activities that should be scalable at European level and demonstrate their strong EU added value;\n• Explain its links to the New European Innovation Agenda and how the project will contribute to its objectives;\n• Explain how the proposed action plans complement and reinforce their national and/or regional and/or local innovation plans, policies and/or strategies in synergy, including with their smart specialisation strategies, and if applicable their Partnerships for Regional Innovation and start-up villages[6];\n• Explain the process that they plan to follow, with an open, clear, realistic, and impact-oriented approach, including relevant guidance mechanisms and tools;\n• Present what common knowledge assets are expected from the proposed action plans, and the benefit of the intended beneficiaries of the plans;\n• Present the targeted milestones to be achieved.\nThe proposals for the development of a joint long-term action plan may include the following two (2) phases:\n• A first phase to foster close dialogue among key stakeholders for strategy/partnership building, mapping, and analysis of existing national and/or regional and/or local innovation agendas/strategies/policies/plans/activities, including local pockets of excellence/innovation hubs, the relevant active/inactive actors (including financial actors, citizens, and individual innovators) and ways to motivate their inclusion, identification of areas of competitive advantage for sustainable economic growth, mapping of gaps, needs, and opportunities. 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{"id":"101207066","acronym":"RESISTTE","name":"Development and validation of simulation-based stress test for resilience assessment in manufacturing companies","offer":"The objective of RESISTTE  is to develop and validate a scalable banking-inspired simulation-based stress test tool for shop floor resilience assessment under realistic disruption scenarios, considering 6 disruption effects. It will be realized by:- Creating a generally applicable model for shop floor resilience assessment inspired by the stress test approach for European banks. This includes European Banking Authority stress test methodology analysis and its relevant elements integration with simulation components for basic shop floor and logistics processes, disruption effects dynamics, and recovery actions.- Training an existing Large Language Model, for predicting the regions- and manufacturing fields-based probability of various types of external disruptions. LLM will be contextualized and feed with a news database. Retrieved next period disruption predictions will be converted into shop floor disruption effects providing input for realistic simulation scenarios.- Implementing and validating the simulation-based stress test tool prototype that integrates stress scenario prediction application to the shop floor resilience assessment model. This includes the computational simulation of manufacturing processes, disruption effects and recovery actions according to the developed model. The tool will be first tested in laboratory environment and thereafter in industrial settings. Such simulation-based resilience assessment tool will be efficient tool for manufacturing managers and CEOs for mapping the shortcomings and planning new investments and changes for increasing the shop floor resilience level. 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This will help spread excellence and close the still apparent research and innovation gap within Europe.\nGlobal Fellowships are based on a secondment to a third country and a mandatory 12 month return period to a European host. The researcher must comply with the rules of mobility in the country where the Global Fellowship secondment takes place, not for the country of the return phase.\nResearchers receiving an Individual Fellowship may opt to include a secondment phase in Europe, notably in the non-academic sector, within the overall duration of their fellowship. For a fellowship of 18 months or less, the secondment phase may last up to three months. For a fellowship of more than 18 months, the secondment phase may last up to six months. The secondment phase can be a single period or be divided into shorter mobility periods. The secondment should significantly add to the impact of the fellowship. 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{"id":"101278807","acronym":"MarkovForScreening","name":"Risk-Stratified and Personalized Cancer Screening with Bidirectional Multistate Markov Models","offer":"Multistate Markov Models (MMM) are powerful tools for analyzing the progression of diseases through different stages, particularly in oncology. Recent studies have modeled stage transition probabilities as functions of multimodal, time-dependent biomarkers to enable predictions based on histopathological features. However, current MMM approaches often overlook the reverse relationship—that is, the influence of the disease stage on the evolution of time-dependent biomarkers. At worst, this omission leads to misspecification bias, at best we miss the opportunity of a better modeling. In this proposal, I aim to address this gap by developing MMM methodologies that explicitly account for the bidirectional relationship between stage progression and associated time-dependent covariates, I call them bidirectional-MMM (bi-MMM). This research is particularly relevant in cancer screening contexts, where a patient's cancer stage influences treatment decisions and, consequently, the trajectory of their biomarkers, which might be high-dimensional and missing at random. A more accurate representation of cancer progression enables the design of personalized screening protocols, thereby improving the harm-to-benefit ratio and reducing the risk of overdiagnosis –when a patient is heavily treated for a cancer that would not have caused symptoms or harm during their lifetime. Overdiagnosis is particularly prevalent in prostate cancer screening compared to other cancer screening programs, even though prostate cancer is the most common cancer among men in Western countries. The supervisors of this project, Prof. Auvinen and Prof. Nevalainen, are currently leading an innovative prostate cancer screening initiative at Tampere University, in alignment with European health policy goals. 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Budget-Based"],"status":"Closed","openingDate":"2022-12-14","deadlineDates":["2023-03-14"],"budget":{"budgetByYear":{"2023":"9000000"},"expectedGrants":3,"minContribution":2000000,"maxContribution":3000000,"deadlineModel":"single-stage"},"keywords":["Energy efficient buildings","Other social sciences","Social enterprises"],"description":"Expected Outcome:\nProjects should contribute to all of the following expected outcomes:\n• Provide guidance on effective measures that can increase the socio-economic integration of marginalised communities, migrants, refugees and disadvantaged groups by reducing housing inequalities and improving access to quality housing.\n• Provide policymakers with a comprehensive overview of how income and wealth polarisation affect the housing market against the background of changing interest rates and inflation.\n• Support policymakers in better understanding how the green and digital transition could affect housing inequalities and how “supply-side” land use policies as well as social innovation could help address such inequalities in a sustainable way.\n• Provide local and regional policymakers with guidance based on best practices to support the development of affordable and inclusive housing facilities, including energy efficient housing.\nScope:\nAccess to affordable and social housing as well as homelessness remain challenges to foster social inclusion and tackle entrenched poverty across Europe. Energy poverty affects nearly 34 million Europeans who are unable to afford keeping their homes warm. Housing prices have been steadily growing every year and faster than disposable income. Housing is now the highest item of expenditure for European citizens.\nThe top 1% wealth shares have risen again recently in Europe, and the gap between asset owners and pure income earners and social transfer recipients is increasing further. During the COVID, high-income workers suffered limited income losses and often increased their savings compared to low-income workers for which the opposite holds. These trends are likely to bring about house purchases (sales) from high-income (low-income) households, reinforcing wealth inequalities in the housing component. Research may provide a mapping of recent household wealth dynamics and their segregation implications.\nThe European Green Deal will affect housing markets notably through the Renovation wave and its Affordable Housing Initiative as well as through the revision of the Energy Efficiency and the Energy Performance of Buildings Directives. Increasing the energy efficiency of buildings helps tackling energy-poverty. Research may inform policy measures that ensure energy efficiency and affordable housing go hand in hand and are accessible to all socio-economic groups. Interlinks between housing inequalities and carbon inequalities as well as mobility poverty are of interest too. Research may focus on the relation between housing inequalities and the labour mobility from regions facing job losses to regions generating new jobs in the context of the twin transition. With regard to social and affordable housing, research may shed light on the role social, green and digital innovations can play in addressing housing inequalities.\nInterlinkages between the digital and green transition, sustainable spatial planning, economic regeneration and housing inequalities merit more attention. Links between workplace and housing inequality are multidimensional, with structural conditions, working conditions and family conditions playing important roles. Housing inequalities should not lead to new forms of discrimination in labour markets. Research may inform policy actions to ameliorate the organisation of work from home, notably for vulnerable households. New forms of work could also impact preferences for rental housing compared to homeownership. Research may also look at the role of social economy actors in addressing housing inequalities while stimulating inclusion, economic and social development.\nResearch should make a granular assessment of these issues for different geographical areas, degrees of urbanisation, tenure statuses and different household’s compositions. The gender and intergenerational dimensions are essential. Clustering and cooperation with other selected projects under this call and other relevant projects are strongly encouraged.","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-CL2-2023-TRANSFORMATIONS-01-09"}]}}
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The scheme particularly supports the return and (re)integration of European researchers from outside Europe and those who have previously worked here, as well as researchers displaced by conflict outside the EU and Horizon 2020 Associated Countries. It also promotes the career restart of individual researchers who show great potential.\nScope:Support is foreseen for individual, trans-national fellowships awarded to the best or most promising researchers of any nationality, for employment in EU Member States or Horizon 2020 Associated Countries. It is based on an application made jointly by the researcher and the beneficiary in the academic or non-academic sectors.\nOnly one proposal per individual researcher per call will be evaluated.\nFellowships take the form of European Fellowships or Global Fellowships. European Fellowships are held in EU Member States or Horizon 2020 Associated Countries and are open to researchers either coming to Europe from any country in the world or moving within Europe. The researcher must comply with the rules of mobility in the country where the European Fellowship is held.\nDirect return to and long-term reintegration of researchers in Europe, including in their country of origin, is supported via a separate multi-disciplinary reintegration panel of the European Fellowships. For the reintegration panel, there must be direct mobility to the country of the beneficiary in Europe from a third country (compulsory national service and/or short stays such as holidays are not taken into account).\nSupport to individuals to resume research in Europe after a career break, e.g. after parental leave or due to recent migration, is ensured via a separate multi-disciplinary career restart panel of the European Fellowships. To qualify for the career restart panel, researchers must not have been active in research for a continuous period of at least 12 months within the 18 months immediately prior to the deadline for submission.\nResearchers seeking to work on research and innovation projects in an organisation from the non-academic sector will be supported via a separate multi-disciplinary society and enterprise panel of the European Fellowships. The objective of this panel is to facilitate career moves between the academic and non-academic sectors, to stimulate innovation, and to open attractive career opportunities for researchers outside academia.\nThe Widening Fellowships implemented through Work Programme part 15, Spreading Excellence and Widening Participation, provide specific support to researchers to undertake their fellowship in a widening country[1]. This will help spread excellence and close the still apparent research and innovation gap within Europe.\nGlobal Fellowships are based on a secondment to a third country and a mandatory 12 month return period to a European host. The researcher must comply with the rules of mobility in the country where the Global Fellowship secondment takes place, not for the country of the return phase.\nResearchers receiving an Individual Fellowship may opt to include a secondment phase in Europe, notably in the non-academic sector, within the overall duration of their fellowship. For a fellowship of 18 months or less, the secondment phase may last up to three months. For a fellowship of more than 18 months, the secondment phase may last up to six months. The secondment phase can be a single period or be divided into shorter mobility periods. The secondment should significantly add to the impact of the fellowship. In the Global Fellowships, such a secondment can also take place at the start of the action at the beneficiary or a partner organisation in Europe for a maximum of 3 months, allowing the researcher to spend time there before moving on to a partner organisation in a third country.\nA Career Development Plan should be established jointly by the supervisor(s) and the researcher. In addition to research or innovation objectives, this plan comprises the researcher's training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences.\nResearchers participating in the Individual Fellowships may opt to work part-time in order to pursue supplementary activities. These might include creating a company, or engaging in advanced studies not related to the MSCA grant. 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{"id":"101043356","acronym":"PROGRESS","name":"Reading provenance from ubiquitous quartz:  understanding the changes occurring in its lattice defects in its journey in time and space by physical methods","offer":"Quantitative provenance analysis studies are instrumental in understanding the tectonic and climatic processes that are shaping Earth`s landscape. Although the most abundant mineral in the sedimentary system is quartz, almost all studies in provenance analysis investigate accessory minerals. Quartz crystals contain a vast number of point defects, intrinsic or due to impurities. Although our understanding on the formation and dynamics of these defects is far from complete, a few of these defects in quartz are used for dating Quaternary sediments by luminescence (thermoluminescence (TL) or optically stimulated luminescence (OSL)) or by electron spin resonance (ESR).  PROGRESS aims at proving that point defects in quartz have also the capacity to carry genetic information and their modifications can provide evidence for antiquity, metamorphism (or lack thereof) as well as knowledge on weathering, transport, or recycling. This information can be unravelled by ESR and luminescence methods in combination with microscopic techniques such as scanning electron microscopy coupled with cathodoluminescence (CL) wavelength resolved spectroscopy. To understand changes that are occurring at atomic level in quartz in nature in geological time, PROGRESS will investigate quartz grains extracted from independently dated old to young quartz-bearing continental crustal sources, metamorphosed rocks versus their unmetamorphosed equivalents, fresh versus highly weathered samples, as well as intrusive versus volcanic rocks, besides conducting experiments in laboratory environments. To tackle nature`s complexity during sediment movement in space and time the effect of physical and chemical changes that occur during transport of quartz grains will be investigated by the study of river sediments that drain different lithologies. These investigations will allow a simple quartz based fingerprinting method to be developed, that will have a significant impact on quantitative provenance studies.","objective":"Quantitative provenance analysis studies are instrumental in understanding the tectonic and climatic processes that are shaping Earth`s landscape. Although the most abundant mineral in the sedimentary system is quartz, almost all studies in provenance analysis investigate accessory minerals. Quartz crystals contain a vast number of point defects, intrinsic or due to impurities. Although our understanding on the formation and dynamics of these defects is far from complete, a few of these defects in quartz are used for dating Quaternary sediments by luminescence (thermoluminescence (TL) or optically stimulated luminescence (OSL)) or by electron spin resonance (ESR).  PROGRESS aims at proving that point defects in quartz have also the capacity to carry genetic information and their modifications can provide evidence for antiquity, metamorphism (or lack thereof) as well as knowledge on weathering, transport, or recycling. This information can be unravelled by ESR and luminescence methods in combination with microscopic techniques such as scanning electron microscopy coupled with cathodoluminescence (CL) wavelength resolved spectroscopy. 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{"id":"101328775","acronym":"iNAMed","name":"Translating In Silico NAMs into Regulatory Practice for Medical Devices","offer":"iNAMed aims to establish a precedent for integrating in silico New Approach Methodologies (NAMs) into the conformity assessment of medical devices under MDR (EU 2017/745). Although AI-driven computational toxicology has reached high scientific maturity, its regulatory uptake remains limited due to insufficient validation, lack of structured benchmarking and absence of formal integration pathways. 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Activities must cover a number of the following elements:\n• Benchmarking the NAMs against state-of-the-art animal models and/or human trials\n• Demonstration in relevant application, such as disease modelling, or testing of medicinal products and medical technologies for safety, efficacy, or quality\n• Organisation of consultation meetings/workshops with industrial end users, regulators, CROs (Contract Research Organisations), standard setting bodies or other relevant stakeholders to gather further needs and feedback\n• Engagement with infrastructures for testing and data collection as testing and validation of the NAM outside the developer’s lab\n• Development of regulatory-grade data packages suitable for submission to relevant agencies (e.g. EMA, FDA, OECD), and\n• Documentation on scalability, standardisation, and potential barriers to uptake.\nDuring the project’s implementation phase, beneficiaries will be encouraged to consider using the EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) of the European Commission’s Joint Research Centre for aspects of standardisation, automation and validation of in vitro methods. These facilities operate and provide support at the interface between pre-normative research, regulatory sciences and innovation.\nScope:\nNew Approach Methodologies (NAMs) have the potential to replace, reduce or refine animal use in the testing96 of medicinal products. Scientific progress in recent decades has delivered several animal-free NAMs that have the potential to transform how we understand human biology and assess the safety, efficacy, and quality testing in the health sector. However, a lack of knowledge, experience and confidence in the use of such novel methodologies has limited their adoption by end users, including, for example, industry and regulators.\nThis Challenge competition therefore looks to accelerate the adoption of NAMs in biomedicine and support companies that want to bring NAMs to the market. 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Hydrogen peroxide is a potent but eco-friendly disinfection agent, yet its use in IWT is very limited due the costs, risks and complexities of its present-day supply chain. HPGen will disrupt today’s H2O2 supply chain, enabling growers to reap the benefits of its use in IWT, substantially decreasing IWT and irrigation line maintenance costs, eliminating use of toxic-chemicals in IWT, improving farm safety, and increasing crop yields. HPGen will provide farmers with a positive economic impact of €4k-€5k per hectare per annum, while enhancing agriculture sustainability and reducing environmental impact. Technology breakthrough was made at the Danish Technical University 5 years ago, and a commercialization path was launched 2 years ago by HPNow ApS, a Danish SME. The company has since been highly successful in scaling up its technology, while attracting strong commercial partners, including global leaders in agriculture irrigation and in bulk hydrogen peroxide production, which are actively supporting this project. This project will initiate with pilot and customer trials of a full-scale version (TRL 6), and will end with commercial launch of HPGen (TRL 9).","objective":"Greenhouses in Europe and Mediterranean produce 30% of the EU’s fruits and vegetables. Growing irrigation water resource pressures are driving greenhouse growers to use of more efficient irrigation techniques, and of non-potable water sources. These lead to a strong need for irrigation water treatment (IWT), to eliminate water-borne plant and human pathogens, mitigate clogging by bio-foul and secure reliable and uniform irrigation, and improve water oxygenation. 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APS","shortName":null,"role":"coordinator","country":"DK","city":"KOBENHAVN","activityType":"PRC","sme":true,"ecContribution":1232391.3,"totalCost":1760559.0,"geolocation":[55.6980542,12.5581246],"order":1}],"topicDetails":[{"identifier":"SMEInst-07-2016-2017","title":"Stimulating the innovation potential of SMEs for sustainable and competitive agriculture, forestry, agri-food and bio-based sectors","callIdentifier":"H2020-SMEInst-2016-2017","callTitle":"Horizon 2020 dedicated SME Instrument 2016-2017","programme":"Horizon 2020 Framework Programme","programmeDivisions":["Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy","Societal Challenges","EC Treaty","Sustainable and competitive bio-based industries and supporting the development of a European bio-economy","Sustainable agriculture and forestry","Industrial Leadership"," Sustainable and competitive agri-food sector for a safe and healthy diet"," Mainstreaming SME support, especially through a dedicated instrument","Innovation in SMEs"],"typeOfAction":"SME-1 SME instrument phase 1","typeOfMGA":[],"status":"Closed","openingDate":null,"deadlineDates":[null,null,null,null,null,null,null,null],"budget":{"budgetByYear":{"2016":2545545.4,"2017":3787009.4},"expectedGrants":null,"minContribution":null,"maxContribution":null,"deadlineModel":"multiple cut-off"},"keywords":[],"description":"Specific Challenge:SMEs can play a crucial role in developing resource-efficient and cost-effective solutions to secure sufficient supplies of safe, healthy and high quality food and other bio-based products, by developing productive, sustainable and resource-efficient primary production systems, fostering related ecosystem services and the recovery of biological diversity, alongside competitive and low-carbon supply, processing and marketing chains. Actions under this topic are expected to contribute to one or a combination of several challenges addressed by Societal Challenge 2 of Horizon 2020 with regard to terrestrial resources (i.e. 2.1 ' Sustainable agriculture and forestry', 2.2 ' Sustainable and competitive agri-food sector for a safe and healthy diet' and 2.4 ' Sustainable and competitive bio-based industries and supporting the development of a European bioeconomy'). Particular attention should be given to :\n• Advancing innovations in Integrated Pest Management\n• Resource-efficient eco-innovative food production and processing\n• Reduction of food losses and waste on farm and along the value-chain\n• Creating added value from waste and by-products generated on farm and along the value-chain\nScope:The SME instrument consists of three phases, including a coaching and mentoring service for beneficiaries. Participants can apply to phase 1 or directly to phase 2.\nIn phase 1, a feasibility study shall be developed in order to verify the technological/practical as well as economic viability of an innovation idea/concept with considerable novelty to the industry sector in which it is presented (new products, processes, design, services and technologies or new market applications of existing technologies). The activities could, for example, comprise risk assessment, market study, user involvement, Intellectual Property (IP) management[1],\ninnovation strategy development, partner search, feasibility of concept and the like to establish a solid high-potential innovation project aligned to the enterprise strategy and with a European dimension. Bottlenecks in the ability to increase profitability of the enterprise through innovation shall be detected and analysed during phase 1 and addressed during phase 2 to increase the return in investment in innovation activities. The proposal should contain an initial business plan based on the proposed idea/concept. It should outline the specifications of a more elaborate business plan, which is to be the outcome of the project, and the criteria for success.\nFunding will be provided in the form of a lump sum of EUR 50.000. Projects should last around 6 months.\nIn phase 2, innovation projects[2]\nwill be supported that address the specific challenges identified and that demonstrate high potential in terms of company competitiveness and growth underpinned by a strategic business plan. Activities should focus on innovation activities such as demonstration, testing, prototyping, piloting, scaling-up, miniaturisation, design, market replication and the like aiming to bring an innovation idea (product, process, service etc.) to industrial readiness and maturity for market introduction, but may also include some research. For technological innovation, Technology Readiness Levels of 6 or above (or similar for non-technological innovations) are envisaged; please see part G of the General Annexes.\nProposals shall be based on an elaborate business plan. Particular attention must be paid to IP protection and ownership; applicants will have to present convincing measures to ensure the possibility of commercial exploitation ('freedom to operate').\nProposals shall contain a specification for the outcome of the project and criteria for success. They will include an explanation of how the results of the supported project are to be commercialised and of what kind of impact on the company is expected.\nThe Commission considers that proposals requesting a contribution from the EU of between EUR 0.5 and 2.5 million[3]\nwould allow phase 2 to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts (higher or lower). Projects should last between 12 and 24 months. [4]\nPhase 3 of the SME Instrument aims to increase the economic impact of the funding provided by the SME Instrument phase 1&2 grants and by the business coaching. Phase 3 is not subsequent to phase 1 and/or 2, but provides specific support to SME instrument beneficiaries during and after phase 1 or 2.\nAll support under phase 3 of the SME instrument will be accessible through a single, dedicated entry point, which will serve as an information portal and a networking space.\nThis platform will offer access to two main strands of services:\n• Access to markets\n• Access to finance\nIn addition, phase 3 will create opportunities for partnering, networking and training, which are set out in the Dedicated Support Actions at the end of this call.\nSME Instrument beneficiaries are also offered dedicated business innovation coaching and mentoring support. This service is facilitated by the Enterprise Europe Network and delivered by a dedicated coach through consultation and signposting to the beneficiaries. The coaches are recruited from a central database managed by the Commission and have all fulfilled stringent criteria with regards to business experience and competencies.\nThroughout the three phases of the instrument, the Network will complement the coaching support by providing access to its innovation and internationalisation service offering. This could include, for example, depending on the need of the SME, support in identifying growth potential, developing a growth plan and maximising it through internationalisation; strengthening the leadership and management skills of individuals in the senior management team and developing in-house coaching capacity; developing a marketing strategy or raising external finance.\nExpected Impact:  • Enhancing profitabili","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/SMEInst-07-2016-2017"}]}}
{"id":"101283567","acronym":"KLEBSCELL","name":"Exploiting intra-species diversity to identify genomic properties that affect the cell biology, proliferation and pathogenicity of Klebsiella pneumoniae","offer":"Klebsiella pneumoniae is an opportunistic pathogen that can cause particularly serious disease and mortality in immune-compromised, elderly, or otherwise vulnerable individuals. A high burden of mortality is attributed to K. pneumoniae: a 2019 study estimated that K. pneumoniae was associated with 790.000 deaths that year. Due to its incidence, mortality, and growing antibiotic resistance, the World Health Organization placed K. pneumoniae at the top of the Bacterial Priority Pathogens List in 2024, highlighting its danger to public health. Despite the high healthcare burden posed by K. pneumoniae, it remains a rather understudied pathogen, particularly regarding non-canonical virulence factors. Antibiotic resistance, for example, is rather well-studied in the pathogen, but our understanding of K. pneumoniae physiology, including the keys to its growth, replication, and survival in diverse environments is limited. K. pneumoniae displays extensive intra-specific diversity, with its pangenome encoding close to 30.000 protein-coding sequences. The general goal of this proposal is to exploit the extensive intra-species diversity of K. pneumoniae to determine how specific genomic properties affect cellular physiology, contribute to growth and proliferation, and underlie pathogenicity. The functional role of selected regions will subsequently be determined in more detail. K. pneumoniae intraspecific diversity will be investigated using a library of 100-200 strains across different growth conditions and antibiotics. A high-throughput cell imaging system will be used to collect various phenotypic measures. Next, genomic studies will uncover genetic differences among the strains, and these differences will be connected to phenotype. Finally, genetic manipulation will be used to confirm the effect of these genetic differences. Such knowledge about the pathogen’s genetic components for success is important in managing K. pneumoniae infections more effectively in the future.","objective":"Klebsiella pneumoniae is an opportunistic pathogen that can cause particularly serious disease and mortality in immune-compromised, elderly, or otherwise vulnerable individuals. A high burden of mortality is attributed to K. pneumoniae: a 2019 study estimated that K. pneumoniae was associated with 790.000 deaths that year. Due to its incidence, mortality, and growing antibiotic resistance, the World Health Organization placed K. pneumoniae at the top of the Bacterial Priority Pathogens List in 2024, highlighting its danger to public health. Despite the high healthcare burden posed by K. pneumoniae, it remains a rather understudied pathogen, particularly regarding non-canonical virulence factors. Antibiotic resistance, for example, is rather well-studied in the pathogen, but our understanding of K. pneumoniae physiology, including the keys to its growth, replication, and survival in diverse environments is limited. K. pneumoniae displays extensive intra-specific diversity, with its pangenome encoding close to 30.000 protein-coding sequences. The general goal of this proposal is to exploit the extensive intra-species diversity of K. pneumoniae to determine how specific genomic properties affect cellular physiology, contribute to growth and proliferation, and underlie pathogenicity. The functional role of selected regions will subsequently be determined in more detail. K. pneumoniae intraspecific diversity will be investigated using a library of 100-200 strains across different growth conditions and antibiotics. A high-throughput cell imaging system will be used to collect various phenotypic measures. Next, genomic studies will uncover genetic differences among the strains, and these differences will be connected to phenotype. Finally, genetic manipulation will be used to confirm the effect of these genetic differences. Such knowledge about the pathogen’s genetic components for success is important in managing K. pneumoniae infections more effectively in the future.","sourceVersion":"c7784a45eb6ab9ad8976f2c177d36600ec3a06d1660f280b86b80f849c6b0549","originalSourceVersion":"af42002dda84549a44faae58c4c03b23ef9816234a22924c9b9cf73e0d13df70","textHash":"f460577778a7d963bc62284948873f10f314808991960e5454285e6e3fcdaa9a","sourceUrl":"https://cordis.europa.eu/project/id/101283567","country":"BE","participantCountries":["BE"],"programme":"HORIZON","status":"SIGNED","sourceUpdated":"2026-03-21 05:52:15","locations":[],"goal":3,"goalIds":[3],"rels":[{"code":"3","name":"Ensure healthy lives and promote well-being for all at all ages","uri":"http://data.europa.eu/sdg/3","state":"supported","strength":"strong","assertionId":"mapping:0e04ad17088de09359ff97b68b30058323da2e5358615603a5ff57483b353b05","revision":1,"reviewStatus":"unreviewed","claim":"Project source excerpt (planned): “pneumoniae infections more effectively in the future.”","modality":"planned","hypothesis":null,"quote":"Such knowledge about the pathogen’s genetic components for success is important in managing K.\n\npneumoniae infections more effectively in the future.\n\nKlebsiella pneumoniae is an opportunistic pathogen that can cause particularly serious disease and mortality in immune-compromised, elderly, or otherwise vulnerable individuals.\n\nA high burden of mortality is attributed to K.\n\npneumoniae: a 2019 study estimated that K.\n\npneumoniae was associated with 790.000 deaths that year.\n\nDue to its incidence, mortality, and growing antibiotic resistance, the World Health Organization placed K.\n\npneumoniae at the top of the Bacterial Priority Pathogens List in 2024, highlighting its danger to public health.\n\nDespite the high healthcare burden posed by K.\n\npneumoniae, it remains a rather understudied pathogen, particularly regarding non-canonical virulence factors.\n\nAntibiotic resistance, for example, is rather well-studied in the pathogen, but our understanding of K.\n\npneumoniae physiology, including the keys to its growth, replication, and survival in diverse environments is limited.\n\nK.\n\npneumoniae displays extensive intra-specific diversity, with its pangenome encoding close to 30.000 protein-coding sequences.\n\nThe general goal of this proposal is to exploit the extensive intra-species diversity of K.\n\npneumoniae to determine how specific genomic properties affect cellular physiology, contribute to growth and proliferation, and underlie pathogenicity.\n\nThe functional role of selected regions will subsequently be determined in more detail.\n\nK.\n\npneumoniae intraspecific diversity will be investigated using a library of 100-200 strains across different growth conditions and antibiotics.\n\nA high-throughput cell imaging system will be used to collect various phenotypic measures.\n\nNext, genomic studies will uncover genetic differences among the strains, and these 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Grant"],"status":"Closed","openingDate":"2025-04-09","deadlineDates":["2025-09-10"],"budget":{"budgetByYear":{"2025":"60643921"},"expectedGrants":0,"minContribution":0,"maxContribution":0,"deadlineModel":"single-stage"},"keywords":[],"description":"Expected Outcome:\nProject results are expected to contribute to the following outcomes:\nFor supported postdoctoral fellows\n• Increased set of research and transferable skills and competences, leading to improved employability and career prospects of MSCA postdoctoral fellows within academia and beyond;\n• New mind-sets and approaches to R&I work forged through international, inter-sectoral and interdisciplinary experience;\n• Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.\nFor participating organisations\n• Increased alignment of working conditions for researchers in accordance with the principles set out in the European Charter for Researchers;\n• Enhanced quality and sustainability of research training and supervision;\n• Increased global attractiveness, visibility and reputation of the participating organisation(s);\n• Stronger R&I capacity and output among participating organisations; better transfer of knowledge;\n• Regular feedback of research results into teaching and education at participating organisations.\nScope:\nFellowships will be provided to excellent researchers undertaking international mobility. Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.\nPostdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:\n• European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.\n• Global Postdoctoral Fellowships are open to European nationals or long-term residents[1] who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. These fellowships require an outgoing phase of minimum 12 and maximum 24 months in a non-associated Third Country, and a mandatory 12-month return phase to a host organisation based in an EU Member State or a Horizon Europe Associated Country.\nSpecific eligibility conditions apply to MSCA Postdoctoral Fellowships in the research areas covered by the Euratom Research and Training Programme 2021-2025[1].\nSecondments\nResearchers receiving a Postdoctoral Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.\nFor European Postdoctoral Fellowships, secondments cannot exceed one third of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.\nFor Global Postdoctoral Fellowships, optional secondments are permitted for up to one third of the outgoing phase. A maximum of three months of such secondments can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.\nSecondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.\nPlacements in the non-academic sector\nPostdoctoral Fellowships can provide an additional period of up to six months to support researchers opting for a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country[3]. While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country[4]. The request for such a non-academic placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.\nIf the placement does not meet the requirements (taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. 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The ability to individualize the work practices within a business process and the possibility of starting modeling from a local rather than a global point of view are the core properties that distinguish subject-oriented business process modeling from other approaches that focus on the sequence of activities rather than the flow of communication.The acquisition of work process knowledge, however, has hardly been addressed methodologically and technically so far. Following the individual-centered philosophy of S-BPM, work process knowledge should be captured and reflected upon in the current work situation of an individual or a group of individuals collaborating, enabling them to set up or revise the work practices whenever the need arises.IANES addresses the requirement of in-situ process knowledge acquisition and negotiation. The goal of the project is to provide a set of methods and tools, than enables the members of an organization to externalize, reflect, transfer and align their knowledge about individual work practices and interfaces to co-workers. Ultimately, people will be able to use the existing enactment module to support their individual work practices, dynamically adapt, revise and orchestrate them with others according to current needs. The combination of empowering individuals and local collaboration on an operative level together with maintaining a global view of given business goals and fundamental value creation chains enables organizations to more rapidly and effectively adapt to dynamically changing business environments.\"\"","objective":"Subject-oriented Business Process Management (S-BPM) enables organizations to model and support their business processes along the flow communication among subjects (entities in an organization) rather than focusing on the global control flow like in traditional approaches (e.g. ARIS).People can thus describe their actual ways of performing tasks and are only required to know and describe their interfaces to other subjects. 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The role of SMEs to meet these challenges in all the areas of the Transport Specific Programme[1] is critical as they are key players in the supply chains. Enhancing the involvement of weaker players in innovation activities as well as facilitating the start-up and emergence of new high-tech SMEs is of paramount importance. SMEs are pivotal for delivering the innovations needed for greater sustainable and smarter mobility, better accessibility and logistics serving business and citizens, and thus higher economic growth, in a context where the majority of population lives in urban and urbanised areas. Actions to develop new services, products, processes, technologies, systems and combinations thereof that contribute to achieving the European transport and mobility goals defined in the 2011 Transport White Paper could be particularly suited for this call.\nScope:The SME instrument consists of three phases, including a coaching and mentoring service for beneficiaries. Participants can apply to phase 1 or directly to phase 2.\nIn phase 1, a feasibility study shall be developed in order to verify the technological/practical as well as economic viability of an innovation idea/concept with considerable novelty to the industry sector in which it is presented (new products, processes, design, services and technologies or new market applications of existing technologies). The activities could, for example, comprise risk assessment, market study, user involvement, Intellectual Property (IP) management[2],\ninnovation strategy development, partner search, feasibility of concept and the like to establish a solid high-potential innovation project aligned to the enterprise strategy and with a European dimension. Bottlenecks in the ability to increase profitability of the enterprise through innovation shall be detected and analysed during phase 1 and addressed during phase 2 to increase the return in investment in innovation activities. The proposal should contain an initial business plan based on the proposed idea/concept. It should outline the specifications of a more elaborate business plan, which is to be the outcome of the project, and the criteria for success.\nFunding will be provided in the form of a lump sum of EUR 50.000. Projects should last around 6 months.\nIn phase 2, innovation projects[3]\nwill be supported that address the specific challenges identified and that demonstrate high potential in terms of company competitiveness and growth underpinned by a strategic business plan. Activities should focus on innovation activities such as demonstration, testing, prototyping, piloting, scaling-up, miniaturisation, design, market replication and the like aiming to bring an innovation idea (product, process, service etc.) to industrial readiness and maturity for market introduction, but may also include some research. For technological innovation, Technology Readiness Levels of 6 or above (or similar for non-technological innovations) are envisaged; please see part G of the General Annexes.\nProposals shall be based on an elaborate business plan. Particular attention must be paid to IP protection and ownership; applicants will have to present convincing measures to ensure the possibility of commercial exploitation ('freedom to operate').\nProposals shall contain a specification for the outcome of the project and criteria for success. They will include an explanation of how the results of the supported project are to be commercialised and of what kind of impact on the company is expected.\nThe Commission considers that proposals requesting a contribution from the EU of between EUR 0.5 and 2.5 million[4]\nwould allow phase 2 to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts (higher or lower). Projects should last between 12 and 24 months. [5]\nPhase 3 of the SME Instrument aims to increase the economic impact of the funding provided by the SME Instrument phase 1&2 grants and by the business coaching. Phase 3 is not subsequent to phase 1 and/or 2, but provides specific support to SME instrument beneficiaries during and after phase 1 or 2.\nAll support under phase 3 of the SME instrument will be accessible through a single, dedicated entry point, which will serve as an information portal and a networking space.\nThis platform will offer access to two main strands of services:\n• Access to markets\n• Access to finance\nIn addition, phase 3 will create opportunities for partnering, networking and training, which are set out in the Dedicated Support Actions at the end of this call.\nSME Instrument beneficiaries are also offered dedicated business innovation coaching and mentoring support. 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Copernicus data and information services are available with a free and open data licence.\nCopernicus data is an integral part of the European Data Economy. Europe needs to strengthen its position as provider of products and services based on data, enabling new market opportunities.\nCopernicus data value will be greatly enhanced by its integration with data assets contributed by other vertical domains (i.e. not necessarily from the space/geospatial sector) as well as by leveraging the synergies with EGNOS/Galileo to seize new market opportunities. Many vertical domains, other than space, can benefit from the use of Copernicus.\nMature software technologies such as big data processing and linking technologies, machine learning and artificial intelligence, are widely developed also within the LEIT-ICT Work Programmes of H2020, shall be adopted to offer user-friendly solutions at the scale of the large quantities of data involved. They shall be adopted to contribute to the digitization challenges of the European industry by opening up innovative business avenues and to support societal challenges.\nReal-world industrial/commercial requirements, or societal needs, shall drive the Innovation Actions so that the projects’ results can find their logical path towards market adoption.\nScope:Actions under this topic should be instrumental to help European companies innovate, develop and bring to market new or improved products and services by exploiting Copernicus data assets and, whenever relevant, the link with European satellite positioning/navigation/timing technologies.\nCopernicus data will be at the core of the data value chains and integration activates needed to fulfil the industrial requirements that will drive the proposals.\nProposals should adopt state-of-the-art ICT technologies, such as big data processing and linking technologies, machine learning and artificial intelligence to address the challenges of making sense of large volumes of diverse data from distributed sources, at the scale required to address European and global challenges.\nProposers are strongly encouraged to make use of existing European data infrastructures such as (but not limited to) Copernicus’ DIAS platforms, European open data portals, industrial data platforms, and explore synergies with EGNOS/Galileo signals and services whenever those are relevant. Use and re-use of existing data and computing assets is also strongly recommended.\nThe participation of industry is required to define the project’s industrial requirements from the very beginning of the action and to take ownership of the results.\nEnd users (i.e. professional experts and decision-makers as opposed to researchers or software developers) should also be involved to rigorously test the project’s solutions to make sure the human factor is considered appropriately.\nProposals must demonstrate that they have access to appropriately large, complex and realistic data sets, in addition to Copernicus. The data assets to be used in the Action should be described in the proposal.\nSolid, quantitative and innovative business models should support the proposal giving evidence of the expected industrial, commercial, or societal benefit, and demonstrating a plan towards sustainability after the project’s end.\nA clear distribution of IPRs amongst the members of the consortium is expected.\nFor proposals under this topic:\n• The participation of at least one industrial partner is mandatory, and the participation of SMEs and start-ups is encouraged;\n• Involvement of post-graduate scientists, engineers and researchers and promotion of gender balance is also encouraged, for example through professional work experience or through fellowships/scholarships as applicable;\n• A business plan and evidence of user engagement is compulsory and is to be provided as part of the proposal, to demonstrate the user need and sustainability of the project.\nThe Commission considers that proposals requesting a contribution from the EU of between EUR 1 and 3 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.\nExpected Impact:• Establishment of new sustainable data value chains with Copernicus data at their core with a commercial value;\n• Substantial increase in the market of the number of products and services enabled by integrating Copernicus data across sectors with state-of-the-art innovative technologies, able to generate growth and new jobs;\n• Enhance European industry’s potential to take advantage of market opportunities and establish leadership in the field, as well as boost business activity;\n• Increased market share for European companies in the supply of innovative geospatial products and services.\nCross-cutting Priorities:Blue GrowthSocio-economic science and humanities","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/DT-SPACE-01-EO-2018-2020"}]}}
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Budget-Based"],"status":"Closed","openingDate":"2023-10-17","deadlineDates":["2024-02-22"],"budget":{"budgetByYear":{"2024":"9000000"},"expectedGrants":2,"minContribution":4500000,"maxContribution":4500000,"deadlineModel":"single-stage"},"keywords":["Africa","Economics, Econometrics","Food and beverages","Food safety","Food traceability","International trade"],"description":"Expected Outcome:\nIn line with the European Green Deal priorities and the farm to fork strategy for a fair, healthy and environment‑friendly food system, and in support of the African Continental Free Trade Agreement, the successful proposal will contribute to the AU-EU High Level Policy Dialogue (HLPD) on Science, Technology and Innovation, and its first priority on Food and Nutrition Security and Sustainable Agriculture.\nThe farm to fork strategy aims to accelerate the transition to a sustainable food system that should have a neutral or positive environmental impact, help to mitigate climate change and adapt to its impacts. New opportunities in EU-African trade are opening-up for trade regimes with co-benefits for producers, climate and citizens. Innovative Information and Communications Technology (ICT) based, traceability and certification schemes should maximise co-benefits while helping to keep the effects of Non-Tariff Measures (NTMs) in particular administrative and transaction costs low.\nThe African countries signed the African Continental Free Trade Agreement and launched an action plan for Boosting Intra-African Trade with a view to strengthening regional integration. It is also one of the key priorities of the Africa Agenda 2063 and a major step towards African continental economic integration.\nProject results are expected to contribute to all of the following expected outcomes:\n• Improved assessment systems for sustainable food trade regimes with co-benefits for producers, climate and citizens, biodiversity, assessment of certification schemes (organic, carbon neutral, de-forestation free, conventional), testing innovative solutions with food systems/certification actors;\n• Provide data and recommendations for improved Non-Tariff Measure (NTM) regimes;\n• Provide solutions to food trade, Ministries in charge, border regime management (digital solutions).\nScope:\nProposals are expected to address the following:\n• Study the tipping points to scale-up climate-neutral, fair and just food supply;\n• Explore the climate, biodiversity and social impacts of food supply (organic and conventional) and linked products due to land-use change;\n• Better understanding of the aim, collection, quantification and modelling of NTMs relevant for intra-African and EU-AU trade relations;\n• Clearly explain how the proposal will contribute towards scaling-up of business models of climate-neutral fair and just and efficient food supply;\n• Implement the multi-actor approach by involving a wide range of food system actors and conducting inter-disciplinary research;\n• Link to previous projects on urban – rural food systems for solutions to strengthen resilience of food systems in view of supply and/or price shocks.\nInnovation: Proposals should foresee a space for mentoring and accelerating innovative business concepts, including social innovation and upscaling in view of African or European food business entrepreneurs and start-ups with special consideration of women and the diaspora using cascading funding opportunities. Proposals may involve financial support to third parties e.g. to academic researchers, start-ups, SMEs and other multidisciplinary actors, to, for instance, develop, test or validate developed assessment approaches or collect or prepare data sets or provide other contributions to achieve the project objectives... Consortia need to define the selection process of organisations, for which financial support will be granted. Maximum 20% of the EU funding can be allocated to this purpose.","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-CL6-2024-FARM2FORK-01-11"}]}}
{"id":"101148604","acronym":"DocZow","name":"Documentation of intergenerational transmission in Zoroastrian women's silk weaving","offer":"Zoroastrian women's silk weaving has all the characteristics of intangible cultural heritage","objective":"Zoroastrian women's silk weaving has all the characteristics of intangible cultural heritage","sourceVersion":"cf3470b478d006ea0f46e0fa3bca63b30cc2ebe6a5e31fbc6ff38a93ff422ac4","originalSourceVersion":"746739e41ecf62cff2776542a56b217f8dc4eb41160bc3b70f792897bfafcb1f","textHash":"5890138d698aaa34054cbd095e26b4d260f0167141163f36039d6d1138b2a2fe","sourceUrl":"https://cordis.europa.eu/project/id/101148604","country":"DK","participantCountries":["DK"],"programme":"HORIZON","status":"SIGNED","sourceUpdated":" because it is both traditional, contemporary and alive at the same time, which has been continued through inter generational-transmission. For this reason, this project complements Iran's global registration under the title \"\"Sericulture and traditional production of silk for weaving \"\" by UNESCO in 2022.Chinese silk was imported to Iran through the Silk Road in the Sassanid era, and it led to the establishment of silk textile workshops to supply silk textiles inside and outside of Iran.The official religion during the Sassanid era was Zoroastrianism, but from the beginning of Arab Muslim rule until today, few Zoroastrians have remained. The non-alphabetic language of Zoroastrians is called Dari-Behdini  and half of the speakers are Zoroastrian women, who played the role of bearers and preservers of intangible heritage, oral literature and traditions related to silk textiles from the Sassanid era to the contemporary period and localized the heritage of Chinese silk using the positive aspect of Cultural appropriateness and founded a new form of it.The silk textiles of Zoroastrian women are important from social, cultural and religious aspects:1-The producers and consumers of silk textiles are only women and women have spread and taught it through inter generational-transmission until today. Women have not only been highly successful in retaining and transmitting traditional methods and practices, but also in adapting them in innovative ways with high levels of technical competency. 2-Although silk is a non-native product that came to Iran from another culture, Zoroastrian women turned silk textile products into their cultural capitals and used it as a symbol of cultural identity. 3-Although silk dyeing and using it is associated with obstacles based on the importance of purity  in Zoroastrian religion, but until now, it is used as the only type of Traditional clothes.\"\"","locations":[],"goal":null,"goalIds":[],"rels":[{"code":"11","name":"Make cities and human settlements inclusive, safe, resilient and 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For this reason, this project complements Iran's global registration under the title \"\"Sericulture and traditional production of silk for weaving \"\" by UNESCO in 2022.Chinese silk was imported to Iran through the Silk Road in the Sassanid era, and it led to the establishment of silk textile workshops to supply silk textiles inside and outside of Iran.The official religion during the Sassanid era was Zoroastrianism, but from the beginning of Arab Muslim rule until today, few Zoroastrians have remained. The non-alphabetic language of Zoroastrians is called Dari-Behdini  and half of the speakers are Zoroastrian women, who played the role of bearers and preservers of intangible heritage, oral literature and traditions related to silk textiles from the Sassanid era to the contemporary period and localized the heritage of Chinese silk using the positive aspect of Cultural appropriateness and founded a new form of it.The silk textiles of Zoroastrian women are important from social, cultural and religious aspects:1-The producers and consumers of silk textiles are only women and women have spread and taught it through inter generational-transmission until today. Women have not only been highly successful in retaining and transmitting traditional methods and practices, but also in adapting them in innovative ways with high levels of technical competency. 2-Although silk is a non-native product that came to Iran from another culture, Zoroastrian women turned silk textile products into their cultural capitals and used it as a symbol of cultural identity. 3-Although silk dyeing and using it is associated with obstacles based on the importance of purity  in Zoroastrian religion, but until now, it is used as the only type of Traditional clothes.\"\"","topics":[{"code":"HORIZON-MSCA-2023-PF-01-01","title":"MSCA Postdoctoral Fellowships 2023"}],"legalBasis":[{"code":"HORIZON.1.2","title":"Marie Skłodowska-Curie Actions (MSCA)","main":true}],"euroSciVoc":[{"code":"/31/111/607/1411","path":"humanities/philosophy, ethics and religion/religions/islam","title":"islam"},{"code":"/25/63/399","path":"engineering and technology/materials engineering/textiles","title":"textiles"}],"policyPriorities":{"digitalAgenda":40.0,"cleanAir":40.0,"ai":40.0,"climate":40.0,"biodiversity":0.0},"organisations":[{"name":"KOBENHAVNS UNIVERSITET","shortName":"UCPH","role":"coordinator","country":"DK","city":"KOBENHAVN","activityType":"HES","sme":false,"ecContribution":222240.0,"totalCost":0.0,"geolocation":[55.67452,12.56442],"order":1}],"topicDetails":[{"identifier":"HORIZON-MSCA-2023-PF-01-01","title":"MSCA Postdoctoral Fellowships 2023","callIdentifier":"HORIZON-MSCA-2023-PF-01","callTitle":"MSCA Postdoctoral Fellowships 2023","programme":"Horizon Europe (HORIZON)","programmeDivisions":["Marie Skłodowska-Curie Actions (MSCA)","Excellent Science","Horizon Europe (HORIZON)"],"typeOfAction":"HORIZON-TMA-MSCA-PF-EF HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships","typeOfMGA":["HORIZON Unit Grant"],"status":"Closed","openingDate":"2023-04-12","deadlineDates":["2023-09-13"],"budget":{"budgetByYear":{"2023":"221400000"},"expectedGrants":0,"minContribution":0,"maxContribution":0,"deadlineModel":"single-stage"},"keywords":[],"description":"Expected Outcome:Project results are expected to contribute to the following outcomes:\nFor supported postdoctoral fellows\n• Increased set of research and transferable skills and competences, leading to improved employability and career prospects of MSCA postdoctoral fellows within academia and beyond;\n• New mind-sets and approaches to R&I work forged through international, inter-sectoral and interdisciplinary experience;\n• Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.\nFor participating organisations\n• Increased alignment of working conditions for researchers in accordance with the principles set out in the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers;\n• Enhanced quality and sustainability of research training and supervision;\n• Increased global attractiveness, visibility and reputation of the participating organisation(s);\n• Stronger R&I capacity and output among participating organisations; better transfer of knowledge;\n• Regular feedback of research results into teaching and education at participating organisations.\nScope:Fellowships will be provided to excellent researchers undertaking international mobility. Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.\nPostdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:\n• European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.\n• Global Postdoctoral Fellowships are open to European nationals or long-term residents[1] who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. 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The request for such a non-academic placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.\nIf the placement does not meet the requirements (taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. 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collaboration and creation of common knowledge assets among EU, national, regional and/or local level innovation ecosystems’ stakeholders, enhancing synergies and complementarities of their programmes and encouraging the alignment of their innovation agendas;\n• Ensure the inclusiveness of all key innovation players from across the quadruple helix[1], and all EU territories;\nFoster any other funding leverages, including national or regional public funds, to complement Horizon Europe support for innovation ecosystems.\nScope:\nTarget group(s): National, regional and/or local authorities together with private actors, including public-owned enterprises, and research and innovation actors.\nThe topic will allow national, regional and/or local authorities from Member States, Associated Countries and/or EU regions in charge of innovation policies and programmes, in cooperation with private and research and innovation actors, to prepare joint multi-annual programmes of activities (action 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their long-term commitment; the applicants are encouraged to consider planning commitments of at least five (5) years, towards engaging in the joint cooperation activities set up in the frame of the projects;\n• explain the potential for growth and competitiveness foreseen in the targeted sector and/or expected impact in EU challenge(s) through the proposed cooperation;\n• ensure inclusiveness and diversity with the involvement of all innovation actors applicants, enhance complementarities of EU, national and/or regional funds and programmes and encourage the alignment of their innovation agendas;\n• provide a justification on the need for those joint activities that should be scalable at European level and demonstrate their strong EU added value;\n• explain how the proposed action plans complement and reinforce their national and/or regional and/or local innovation plans, policies and/or strategies in synergy, including with their smart specialisation strategies;\n• explain the 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To that end, proposals under this topic should aim to deliver results that are directed, tailored towards and contributing to most of the following expected outcomes:\n• Academic and industrial developers advance processes that support the timely and robust development of Advanced Therapy Medicinal Products (ATMPs);\n• Manufacturers integrate improved technologies/processes (including Artificial Intelligence solutions), analytic tools, methods including non-clinical methods and assays for more flexible manufacturing of ATMPs;\n• Healthcare providers, researchers and patients get faster access to ATMPs with demonstrated health benefits for unmet medical needs;\n• Companies in the EU and Associated countries get a better market position in the field of ATMP manufacturing and improve their knowledge on how to advance process improvements;\n• The EU and Associated countries lay the foundations for academic centres of excellence[1] in ATMPs.\nScope:\nNew pioneering treatments called Advanced Therapy Medicinal Products (ATMPs)[2], including cell and gene therapies, are at the cutting edge of medicines discovery. Owing to their precise nature, ATMPs embody personalised medicine and reflect a shift in medicine towards potentially one-time curative therapies instead of chronic therapies that mainly cure the symptoms but not the underlying cause of diseases.\nATMPs have undergone important technological advancements that are improving their efficacy, precision, scalability, and safety. Additionally, the disease focus of ATMPs is likely to shift further from rare diseases to more common conditions with larger patient populations. However, the development and manufacturing of ATMPs still faces important challenges, such as long development times, expensive manufacturing processes and a fragmented and dispersed biomanufacturing landscape.\nThe topic focuses on addressing the challenges of ATMP manufacturing, the need for highly specialised equipment and facilities, including in-process quality control and validation tests, scaling up and batch-to-batch reproducibility, whilst maintaining the efficacy of an ATMP product during the manufacturing process and/or the transition from centralised to decentralised manufacturing.\nThis topic aims to optimise the ATMP production where the general manufacturing process for a given medicinal product has already been established but has not been sufficiently optimised for its scale-up. Collaboration is crucial to refine the manufacturing of ATMPs, emphasising advancements in processes - including leveraging the potential of digital tools and advanced sensors -, fostering standardisation and enhancing quality controls for more efficient production and deployment of these innovative therapies, ideally covering the entire manufacturing lifecycle.\nThe proposals should address all the following activities for only one chosen category of ATMP as defined by Regulation 1394/2007 per proposal:\n• Design an improved manufacturing process for ATMPs by:   • Exploring the potential of platform technologies in manufacturing, quality control, non-clinical or clinical testing;\n• Integrating either computational modelling, automation, robotics or digital/Artificial Intelligence solutions with meaningful and measurable impact;\n• Verify the improved performance of the developed process, in comparison to established ones.\n• Demonstrate a reduction in the timeframe and costs of manufacturing while maintaining product quality and standardisation.\n• Demonstrate the translatability, scalability, and robustness of the process suitable for the flexible manufacturing (centralised or decentralised) and deployment of ATMPs by important stakeholders in a patient-centric manner, including the medical community and hospitals.\n• Assess the process and methods developed for their regulatory validity and utility (for example standardised assays including for potency), taking into consideration the potential regulatory impact of the results and, as relevant, develop a regulatory strategy for generating appropriate evidence as well as engaging with regulators in a timely manner.\n• Promote green and sustainable industrial production and minimise environmental impact.\nParticipation of small and medium-sized enterprises (SMEs) is strongly encouraged and proposals should include a commitment for first deployment in the EU.\nWhere relevant, proposals are warmly invited to liaise with the Coordination and Support Action (CSA) project JOIN4ATMP[3], in view of creating complementarities and potential synergies.\nThe Joint Research Centre (JRC) may participate as a member of the consortium selected for funding. 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They are expected to strongly contribute to all challenges outlined in the legal base of the Horizon 2020 Societal Challenge ‘Secure, Clean and Efficient Energy’[1], in particular with regard to\n• Reducing energy consumption and carbon footprint by smart and sustainable use (including energy-efficient products and services as well as ‘Smart Cities and Communities’),\n• Low-cost, low-carbon electricity supply (including renewable energy as well as CCS and re-use),\n• Alternative fuels and mobile energy sources,\n• A single, smart European electricity grid,\n• New knowledge and technologies, and\n• Robust decision making and public engagement.\nScope:The SME instrument consists of three separate phases and a coaching and mentoring service for beneficiaries. Participants can apply to phase 1 with a view to applying to phase 2 at a later date, or directly to phase 2.\nIn phase 1, a feasibility study shall be developed verifying the technological/practical as well as economic viability of an innovation idea/concept with considerable novelty to the industry sector in which it is presented (new products, processes, services and technologies or new market applications of existing technologies). The activities could, for example, comprise risk assessment, market study, user involvement, Intellectual Property (IP) management, innovation strategy development, partner search, feasibility of concept and the like to establish a solid high-potential innovation project aligned to the enterprise strategy and with a European dimension. Bottlenecks in the ability to increase profitability of the enterprise through innovation shall be detected and analysed during phase 1 and addressed during phase 2 to increase the return in investment in innovation activities. The proposal should contain an initial business plan based on the proposed idea/concept.\nThe proposal should give the specifications of the elaborated business plan, which is to be the outcome of the project and the criteria for success.\nFunding will be provided in the form of a lump sum of EUR 50.000. Projects should last around 6 months.\nIn phase 2, innovation projects will be supported that address the specific challenges outlined in the legal base of the Horizon 2020 Societal Challenge ‘Secure, Clean and Efficient Energy’ and that demonstrate high potential in terms of company competitiveness and growth underpinned by a strategic business plan. Activities should focus on innovation activities such as demonstration, testing, prototyping, piloting, scaling-up, miniaturisation, design, market replication and the like aiming to bring an innovation idea (product, process, service etc) to industrial readiness and maturity for market introduction, but may also include some research. For technological innovation a Technology Readiness Levels of 6 or above (or similar for non-technological innovations) are envisaged; please see part G of the General Annexes.\nProposals shall be based on an elaborated business plan either developed through phase 1 or another means. Particular attention must be paid to IP protection and ownership; applicants will have to present convincing measures to ensure the possibility of commercial exploitation ('freedom to operate').\nProposals shall contain a specification for the outcome of the project, including a first commercialisation plan, and criteria for success.\nThe Commission considers that proposals requesting a contribution from the EU of between EUR 0.5 and 2.5 million would allow phase 2 to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts. Projects should last between 12 and 24 months.\nIn addition, in phase 3, SMEs can benefit from indirect support measures and services as well as access to the financial facilities supported under Access to Risk Finance of this work programme.\nSuccessful beneficiaries will be offered coaching and mentoring support during phase 1 and phase 2. This service will be accessible via the Enterprise Europe Network and delivered by a dedicated coach through consultation and signposting to the beneficiaries. The coaches will be recruited from a central database managed by the Commission and have all fulfilled stringent criteria with regards to business experience and competencies. Throughout the three phases of the instrument, the Network will complement the coaching support by providing access to its innovation and internationalisation service offering. 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{"id":"101310748","acronym":"PADSA","name":"PRINTER ACTUATED DEPLOYABLE SOLAR ARRAY - High-power-to-volume, low-cost deployable solar arrays based on a low-temperature in-space 3D printing process","offer":"Traditional deployable solar arrays in space applications are highly inefficient. They are built on Earth before launch. Due to the strict launch requirements, they are constrained by launch-driven design, not in-orbit needs. For small and medium satellite integrators (e.g. mega constellation in LEO), the size, mass, and price of these deployable systems remain prohibitive, limiting available power and raising the total mission cost.At Orbital Matter, we are redefining deployable solar array systems for small and medium platforms through an innovative 3D printing process capable of being used as an ultra-compact and lightweight deployment mechanism, making high-power, low-cost solar arrays accessible to small satellites and cubesats.To simultaneously solve the 3 challenges of manufacturing in outer space (vacuum, microgravity and radiation), we have invented an optimal liquid additive manufacturing process for 3D printing directly in outer space which uniquely combines extrusion-based 3D printing with UV activated liquid polymers.Orbital Matter´s commercial roadmap consists of multiple products with growing functionality over the years that can be divided into 3 categories. The first product category is in-space deployable systems, with the deployable solar array module presented in this proposal as the first product in the portfolio. The same technological concept can be applied in the future to deploy other systems such as antennas, radiators and optics, with similar advantages. Based on this disruptive technology, Orbital Matter's long-term goal is to develop an autonomous in-space construction platform, consisting of 3D printing and robotics capabilities.The main objectives of this EIC Pre-Accelerator proposal are focused on completing the design, manufacturing, assembling and testing an Engineering Model of the complete deployable system in relevant environmental conditions (vacuum and simulated microgravity) to achieve TRL 6.","objective":"Traditional deployable solar arrays in space applications are highly inefficient. They are built on Earth before launch. Due to the strict launch requirements, they are constrained by launch-driven design, not in-orbit needs. 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This includes specific milestones together with concrete and verifiable KPIs to assess progress towards the market.\nThe support will be in awarded by grants max at 70% funding of the eligible costs. 30% co-funding to be covered by the beneficiary through its own resources.\nAn amount between EUR 300.000 and max EUR 500.000 in the form of a lump sum for a period of up to 2 years is considered appropriate.\nSeal of Excellence will be awarded to all proposals that meet the evaluation thresholds but are not funded due to lack of available budget.\nThe requested grant is expected to be used for:\n• addressing the investor and market readiness towards commercialisation and deployment (market research, value proposition, business case and business model, prospects for growth, intellectual property protection, competitor analysis etc.) and if relevant, aspects of regulation, certification and standardisation, aimed at getting both the technology and the business idea investment ready and/or;\n• the maturation and validation of novel technologies beyond proof of concept to viable demonstrators of the technology in the intended field of application (i.e., from minimum TRL 4 up to TRL 6).\nAt the end of the EIC Pre-accelerator project, it needs to:\n• demonstrate that the technology component of their innovation has been tested and validated in a laboratory and other relevant environment (e.g. at least completed all aspects of TRL 5);\n• be ready to apply for EIC Accelerator and/or to seek other investors or sources of funding, to enter licensing or collaboration agreements with third parties, or other routes to market deployment.\nSuccessful applicants and those awarded the Seal of Excellence will be granted free access to the EIC Business Acceleration Services[4], such as coaching and specific events tailored to their needs (e.g. for improving investor and market readiness).\nThis will be complemented by access to the EIC Accelerator Fast Track[5] for submissions to the Accelerator programme following a project review in the second half of the project.\n[1]  Deep-tech ventures have the following characteristics: positioning at the knowledge frontier with long and uncertain R&I cycles; relates to tangible products and industrialisation processes; linked to the ecosystem and especially higher education institutions, problem orientated, or mission driven, focused on the creation of an option space and a dynamic de-risking cycle.\n[2]  Ratio of a firm’s R&D investment to its revenue.\n[3]  Completed TRL 5 (Technology validated in relevant environment – industrially relevant environment in the case of key enabling technologies) or TRL6 (Technology demonstrated in relevant environment -industrially relevant environment in the case of key enabling technologies). 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and enhancing national and regional capacity to address antimicrobial resistance.\n• Progressing towards the achievement of SDG3 ‘Ensure healthy lives and promote well-being for all at all ages’ in sub-Saharan African (SSA) countries;\n• Enable the implementation of the short- and medium-term actions foreseen by the AU EU Innovation Agenda (adopted in July 2023) in the area of public health and the EU Global Health Strategy (November 2022);   • Improve equitable access to a full range of essential health services from health promotion to disease prevention and affordable quality treatment, rehabilitation and palliative care to fight communicable diseases;\n• Expand partnerships based on equal footing, co-ownership, mutual interest and strategic priorities;\n• Provide evidence for informed health policies and guidelines within public health systems in SSA and at international level;\n• Enhance sustainable global scientific collaboration in health research and international cooperation across SSA;\n• Develop novel, innovative HIV therapeutics for reducing the disease burden of HIV in SSA\n• Research on existing Malaria vaccines and development of new promising candidates\n• Accelerating development and integration of therapeutics against neglected tropical diseases (NTDs) in SSA;\n• Tackle Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials\n• Develop new tools, technologies and approaches for vector control in SSA;\n• Develop innovative digital health solutions for SSA.\n• Build appropriate local capacity.\nExpected Outcome:\nThis topic aims at supporting activities that contribute to at least two of the expected impacts for this call. Proposals under this topic should aim at delivering results that are contributing to the following expected outcomes:\n• Accelerate development of therapeutics towards registration to make progress in the control and elimination of NTDs in sub-Saharan Africa;\n• Improve the understanding of barriers for progression of existing and new therapeutics against NTDs through the R&D pipeline;\n• Generate evidence-based recommendations on how to better integrate research and innovation in efficient supply chains for NTDs;\n• Gain a better understanding of different country or region-specific health and research needs, to ensure a better case management of patients with NTDs;\nScope:\nBackground:\nThere is some progress in eliminating and eradicating NTDs as per WHO publication[1] in October 2023: “nineteen countries in Africa have eliminated at least one NTD and there are currently 18 million fewer people requiring interventions against NTDs. Togo achieved a world first by eliminating four NTDs. Guinea worm disease (dracunculiasis) is on the verge of eradication; sleeping sickness (T. b. gambiense human African trypanosomiasis) has been eliminated as a public health problem in seven countries; and the number of reported Buruli ulcer cases decreased by 71% between 2010 and 2021”. However, diseases such as schistosomiasis, onchocerciasis, and other NTDs continue to affect hundreds of millions of people who are most often society’s poorest, in sub-Saharan Africa. The WHO Global report provides information for 2021-2022 on regional progress in Africa NTDs[2].\nMany of NTDs are vector-borne diseases (NTD vector control is in scope of topic HORIZON-JU-GH-EDCTP3-2024-CALL1-01-05 of this call: new tools, technologies and approaches for vector control in sub-Saharan Africa), have animal reservoirs and are associated with complex life cycles. The epidemiology of NTDs is complex and multifactorial, often related to environmental conditions, that makes their public-health control challenging. Moreover, COVID-19 pandemic severely disrupted health systems, including conduct of clinical trials, supply chains for NTD therapeutics and health products and the implementation of prevention strategies. Thus, pharmaceutical interventions combined with interventions such as house improvements, improved access to safe water, sanitation and hygiene (WASH) are also critical in the prevention for the majority of the NTDs, especially[3] for Trachoma, Soil-transmitted helminthiases (STHs), Schistosomiasis and Dracunculiasis.\nScope:\nThe proposals submitted to this call topic are expected to address at least one of the following activities in scope:\n• Conduct clinical trials on therapeutics for NTDs in the scope of the Global Health EDCTP3JU:\nBuruli ulcer, dengue and chikungunya, dracunculiasis (guinea-worm disease), echinococcosis, foodborne trematodiases, human African trypanosomiasis (sleeping sickness), leishmaniases, leprosy (Hansen disease), lymphatic filariasis, mycetoma, onchocerciasis (river blindness), rabies, schistosomiasis, soil-transmitted helminthiases, taeniasis/cysticercosis, trachoma, and yaws. Global Health EDCTP’s remit will not cover chromoblastomycosis and other deep mycoses, scabies and other ectoparasites, and snakebite envenoming.\n• For existing therapeutics for specific indications, there is need to conduct clinical trials of combination therapies against multiple diseases and applicability to vulnerable populations\n• For infections where therapeutics are lacking entirely, clinical trials will be required for the development of new interventions (early stage) or extension of indications (re-purposing)\n• Implementation research of pharmaceutical interventions for several NTDs and, when possible, their mainstreaming into national health systems in combination with other control measures\nWhere possible, collaboration and coordination with the Team Europe ","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-JU-GH-EDCTP3-2024-01-03-two-stage"}]}}
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Then the EIC Accelerator pilot (SME Instrument) is for you.\nThe EIC Accelerator pilot (SME Instrument) supports high-risk, high-potential small and medium-sized enterprises to develop and bring to market new products, services and business models that could drive economic growth.\nThe EIC Accelerator pilot (SME Instrument) is for innovators with ground-breaking concepts that could shape new markets or disrupt existing ones in Europe and worldwide.\nCompetition for support under the EIC Accelerator pilot (SME Instrument) is tough.\nThe EIC Accelerator pilot (SME Instrument) is very selective.\nFollowing the cut-off date of 5 June 2019, only ground-breaking concepts at the last stage before scale-up can be funded.\nThe highest risk, most convincing and excellent proposals can be funded after a thorough evaluation by multinational panels of technology, business and finance experts.\nSelected companies receive business coaching to further develop their innovation idea, and can also receive mentoring. They are helped in networking with other EIC Accelerator pilot (SME Instrument) clients, with other companies of all sizes, and with potential co-investors and follow-up investors across Europe. As an SME Instrument client, you will gain visibility and boost your chances of success in European and international markets.\nEurope needs more radical, market-creating innovations to improve productivity and international competitiveness and generate new jobs and higher standards of living.\nThese innovations must meet user and customer needs and tackle societal, technological and business challenges in a sustainable way.\nHave you got what it takes? Then apply now!\nScope:\nPrinciples and funding of the EIC Accelerator pilot (SME Instrument)\nWho can apply?\nFor-profit SMEs, including young companies and start-ups, from any sector. You must be established in an EU Member State or a Horizon 2020 associated country.\nFollowing the cut-off date of 5 June 2019, only individual[1] for-profit SMEs established in an EU Members State or a Horizon 2020 associated country.\nWhat topics are covered?\nThere are no set topics. Negative impacts on climate and the environment shall be avoided.\nHow does it work?\nThe EIC Accelerator pilot (SME Instrument) provides full-cycle business innovation support. In Phase 2 support is provided in the form of grant only or, following the cut-off date of 5 June 2019, blended finance (combining grant and equity). The EIC Accelerator pilot (SME Instrument) also includes coaching and mentoring.\nFeasibility study: Phase 1\nPhase 1 helps you get a grip on the R&D, technical feasibility and commercial potential of a ground-breaking, innovative idea and develop it into a credible business plan.\nActivities can include, for example, risk assessment, market research, user involvement, analysis of regulatory constraints or standards regimes, intellectual property management, partner search, or feasibility assessment.\nYour goal in Phase 1 is to formulate a solid, high-potential innovation project with a European or global growth-oriented strategy\nYour proposal must be based on an initial business plan and outline the specifications of a more elaborate one, which will be the outcome of the project.\nPhase 1 funding is a lump sum of €50 000[2]. Projects should last around 6 months.\nPlease note Phase 1 will be discontinued[3]. The final deadline for applications will be 5 September 2019.\nFrom concept to market: Phase 2\nPhase 2 helps you develop your business concept further into a market-ready product, service or process aligned with your company's growth strategy. Activities could, for example, include product/service development, trials, prototyping, validation, demonstration and testing in real-world conditions, and market replication. If the activity concerns a primarily technological innovation, a Technology Readiness Level (TRL) of 5/6 or above is required for primarily technological innovation or the equivalent for non-technological innovation. 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