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action","typeOfMGA":[],"status":"Closed","openingDate":null,"deadlineDates":[null],"budget":{"budgetByYear":{"2020":20000000},"expectedGrants":null,"minContribution":null,"maxContribution":null,"deadlineModel":"single-stage"},"keywords":["Networks and information security systems","Software testing processes and tools","Exercise and simulation, training","(user-centric) privacy preservation","Cybersecurity","Digital identity","Integrated systems testing & evaluation","Signature control and signature reduction","Risks and vulnerabilities assessment","Communication technologies","Information technologies","Identity management systems","Simulation tools and technologies","Information management","Security Analysis","Information Security Technologies","Digital services"],"description":"Specific Challenge:In order to minimise security risks, ICT systems need to integrate state-of-the-art approaches for security and privacy management in a holistic and dynamic way. Organisations must constantly forecast, monitor and update the security of their ICT systems, relying as appropriate on Artificial Intelligence and automation, and reducing the level of human intervention necessary.\nSecurity threats to complex ICT infrastructures, which are multi-tier and interconnected, computing architectures, can have multi-faceted and cascading effects. Addressing such threats requires organisations to collaborate and seamlessly share information related to security and privacy management.\nThe increasing prevalence and sophistication of the Internet of Things (IoT) and Artificial Intelligence (AI) broadens the attack surface and the risk of propagation. This calls for tools to automatically monitor and mitigate security risks, including those related to data and algorithms. Moreover, storage and processing of data in different interconnected places may increase the dependency on trusted third parties to coordinate transactions.\nAdvanced security and privacy management approaches include designing, developing and testing: (i) security/privacy management systems based on AI, including highly-automated analysis tools, and deceptive technology and counter-evasion techniques without necessary human involvement; (ii) AI-based static, dynamic and behaviour-based attack detection, information-hiding, deceptive and self-healing techniques; (iii) immersive and highly realistic, pattern-driven modelling and simulation tools, supporting computer-aided security design and evaluation, cybersecurity/privacy training and testing; and (iv) real-time, dynamic, accountable and secure trust, identity and access management in order to ensure secure and privacy-enabling interoperability of devices and systems.\nScope:Proposals are invited to address one of the sub-topics below. In addition, it would be an asset for proposals to include solutions for hands-on and state-of-the-art training, such as cybersecurity exercises.\nFour pilot projects are launched under Horizon 2020 LEIT ICT, as a result of the call H2020-SU-ICT-2018, topic SU-ICT-03-2018 “Establishing and operating a pilot for a Cybersecurity Competence Network to develop and implement a common Cybersecurity Research & Innovation Roadmap”. Proposals should therefore foresee actions to collaborate with these four projects and also with similar ongoing projects funded under H2020, and take account of the results and work done in other relevant H2020 projects on cybersecurity/privacy.\nSME participation is strongly encouraged.\n(a): Dynamic governance, risk management and compliance\nProposals should develop and integrate beyond state-of-the-art approaches to security and privacy management which are: automated, dynamic and adaptive, allowing to identify the vulnerabilities, threats, such as advanced persistent threats, and attacks (including zero-day attacks).\nProposals should include pilots with significant scale involving complex ICT systems and addressing several of the following: forecasting, risk-based situation awareness, evidence-based system and software assessment, visualisation techniques, real-time monitoring and alerts with high level of accuracy, support to fair automated decision-making, run-time adaptation and autonomous recovery from faulty states.\nProposals should address the technical, operational, financial and ethical dimensions of cybersecurity. Concrete application cases should be foreseen. Adapted tools, techniques and formats for collaborative security/privacy event management and reporting should be proposed. Solutions involving advanced, highly representative simulation environments (cyber-ranges) might be proposed.\nThe outcome of the proposal is expected to lead to development up to Technology Readiness level (TRL) 7; please see Annex G of the General Annexes.\nThe Commission considers that proposals requesting a contribution from the EU of between EUR 2 and 5 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.\nType of Action: Innovation Action\n(b): Cyber-threat information sharing and analytics\nProposals should develop and test threat detection frameworks, which should to the extent possible include: (i) collaborative, open, and dynamic repositories of information on threats and vulnerabilities; (ii) build on and update existing ontologies, taxonomies and models; (iii) dynamic tools for automated detection with advanced analytic capabilities, and where possible response and recovery; (iv) accountability and audit techniques; and (v) synchronised real time self- encryption/decryption schemes with recovery capabilities.\nNovel technologies enabling collaboration in cyber threat intelligence and alerting should be proposed, taking into consideration not only technical aspects, but also human aspects such as behavioural patterns, gender differences, privacy, ethics, sovereignty, psychology, linguistic and cultural boundaries.\nThe tools and services that will be developed should be in a position to support the operations of CERTs/CSIRTs and networks of CERTs/CSIRTs. 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Grant"],"status":"Closed","openingDate":"2025-05-06","deadlineDates":["2025-09-24"],"budget":{"budgetByYear":{"2025":"15000000"},"expectedGrants":3,"minContribution":4000000,"maxContribution":5000000,"deadlineModel":"single-stage"},"keywords":[],"description":"Expected Outcome:\nProject results are expected to contribute to all of the following expected outcomes:\n• Climate policies are made more inclusive and equitable, facilitating acceptance across political and societal stakeholders with various socio-economic and development status, both within the EU and globally, enabling high ambition climate action and helping to deliver on the European Green Deal’s commitment to “leave no one behind”;\n• There is an improved consensus between the Global North and the Global South within the UNFCCC process, unlocking a greater momentum in the implementation of the Paris Agreement;\n• The evidence base underpinning IPCC assessments is strengthened, diversified, and made more inclusive, facilitating consensus and government approval processes;\n• Social science perspectives on justice and equity are better incorporated into policy narratives, scenarios, and models, improving their societal relevance and ensuring that climate action strategies are more reflective of the needs, values and concerns of diverse societal groups, building trust in results and outcomes, and increasing their uptake potential.\nScope:\nClimate change and the transition to low-carbon, climate-resilient future raises complex justice questions around equitable sharing of benefits and burdens of mitigation and adaptation efforts. These considerations not only animate global climate negotiations, but also increasingly emerge as a central issue for national politics, legal systems and for the society at large. Fairness thus becomes both a critical enabler and a potential barrier for shaping ambitious climate action, underscoring the need for prioritising research on advancing just climate transitions within the EU and globally.\nFor example, mitigation scenarios that have informed and influenced global climate policymaking and target-setting, and form a vital component of IPCC assessments, have been criticised for not considering fairness more explicitly and systematically, creating a barrier to their acceptance as a basis for global mitigation efforts. On the other hand, to avoid exacerbating existing vulnerabilities and locking into maladaptive pathways, it is also necessary to better account for the justice dimension in adaptation planning and implementation.\nActions should advance more comprehensive and interdisciplinary understanding of climate justice in the context of the European and global mitigation and adaptation policies, promoting awareness, consistency and co-production approaches. They should take into consideration socio-economic, territorial and development disparities that exist between and within countries, regions and across various segments of the population. Actions should address multiple dimensions of justice, diverse spatial and temporal scales (e.g., intergenerational justice), and explore the role of a broad range of social, political, economic, and cultural contexts and factors. These include both collective (such as values, power structures, institutional and legal frameworks, political economy, development models, climate elites) and individual (such as age, gender, and intersectionality) features. Building on the resulting insights, actions are expected to develop recommendations on how to design, implement and evaluate just climate transitions, including definition of specific indicators, standards, and criteria to better operationalise the justice concept in adaptation and mitigation pathways. Among others, actions should address some of the following aspects [1]:\n• Improve integrated assessment models to better represent justice and equity, differences in regional outcomes, and common but differentiated responsibilities and respective capabilities;\n• Enhance clarity, comparability, and transparency across global mitigation scenarios with regard to different justice aspects. Evaluate the feasibility and consistency of regionally differentiated long-term mitigation goals in terms of, for example, investments and financial flows, governance and institutional needs;\n• Analyse distributional aspects of climate policies, assess consequences for well-being and living standards of people from different socio-economic and development contexts. Advance research to assess the needs of and the effects on the most vulnerable and disadvantaged population segments (e.g., elderly, children, women, migrants, minorities, households at risk from energy and/or transport poverty) and sectors, and provide recommendations for corrective measures;\n• Assess the trade-offs and co-benefits between climate action and inequality reduction. Explore the role of inequality and injustice as constraints to individual and collective climate action;\n• Investigate innovative climate policy instruments, initiatives and approaches alternative to those prioritising economic efficiency and propose a broader spectrum of climate policies with more attention to equity. Assess their feasibility;\n• Investigate justice in the context of sectorial transitions, with focus on under-researched (from justice perspective) sectors such as agriculture, forestry and land use;\n• Advance research on how to better account for the needs and constraints of communities representing diversity of vulnerability profiles in disaster risk reduction and adaptation strategies.\nActions should address justice and equity of climate policies both within the EU and from a global perspective, but they may choose to prioritise one of these dimensions, using the other as framing information.\nThe research should be conducted through close collaboration between research teams from Europe and low or middle-income countries, hence international cooperation is required (see eligibility conditions). Moreover, involvement of key stakeholders and regional experts as part of an inclusive process is essential to guarantee that all relevant perspectives are adequately represented. The involvement of civil society is also highly recommended.\nAll p","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-CL5-2025-06-D1-06"}]}}
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My project now builds on the use of somatic variants to reveal the cellular processes that form the brain starting from available human material. Somatic variants will be identified at unprecedent sensitivity in a large set of human foetal tissues, including multiple different brain regions. In work package (WP)1, I will identify and study the lineage segregation steps defining the brain phylogeny starting from the zygote. Mathematical modelling will elucidate mechanisms of clone dynamics. In WP2, I will focus on the cerebral cortex and reconstruct cell phylogenies of neural progenitors and the distribution of cortical clones. Furthermore, I will compare normal versus overgrowth cortical malformation brains, where cell proliferation and migration are altered. In WP3, I will develop new strategies to simultaneously assess cell phylogenies and cell-type specification by identifying somatic variants in multi-omics data. 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These fellowships require an outgoing phase of minimum 12 and maximum 24 months in a non-associated Third Country, and a mandatory 12-month return phase to a host organisation based in an EU Member State or a Horizon Europe Associated Country.\nSpecific eligibility conditions apply to MSCA Postdoctoral Fellowships in the research areas covered by the Euratom Research and Training Programme 2021-2025[1].\nSecondments\nResearchers receiving a Postdoctoral Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.\nFor European Postdoctoral Fellowships, secondments cannot exceed one third of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.\nFor Global Postdoctoral Fellowships, optional secondments are permitted for up to one third of the outgoing phase. A maximum of three months can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.\nSecondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.\nPlacements in the non-academic sector\nPostdoctoral Fellowships can provide an additional period of up to six months to support researchers seeking a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country[3]. While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country[4]. The request for such a placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. It must be substantiated by a letter of commitment from the European non-academic organisation where the placement takes place[5]. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.\nIf the placement does not meet the requirements (missing letter of commitment or taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. This might affect the final score.\nTraining activities\nThe training activities implemented under the Postdoctoral Fellowships should include training for key transferable skills[6], foster innovation and entrepreneurship, (e.g. commercialisation of results, Intellectual Property Rights, communication, public engagement and citizen science) and promote Open Science practices (open access to publications and to research data, FAIR data management, etc.).\nCareer Development Plan\nIn order to equip MSCA postdoctoral fellows with skills that enhance and expand their career opportunities inside and outside academia, a Career Development Plan should be established jointly by the supervisor(s) and the researcher. In addition to research objectives, this plan should comprise the researcher's training and career needs, including training on transferable skills, teaching, plannin","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-MSCA-2022-PF-01-01"}]}}
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These systems will also contribute to new EU strategy for a Sustainable Blue Economy implementation and address the EC Communication Towards a Strong and Sustainable EU Algae Sector,[3] by demonstrating improved environmental performances, maximum resource- and energy-efficiency, and optimal cascading use of bio-based feedstock, aiming for ‘zero waste’ and ‘zero-pollution’ operations. Contribution to the objectives of the R&I Mission ‘Restore our Oceans and Waters by 2030, in particular objective 3 ‘Make the blue economy carbon- neutral and circular’.\nProject results should contribute to the following expected outcomes:\n• Implementation of (environmentally and economically) sustainable micro-algae-based biorefinery processes.\n• Availability of a broader range of micro-algae-based products meeting market requirements.\n• Social acceptance of circular bio-based solutions and products.\n• Decreased energy, water, nutrients and in general resource requirements for micro-algae production and processing with respect to state-of-art.\n• Improved environmental impact with respect to fossil- and/or bio-based state-of-the-art counterparts (if existing).\nScope:The valorisation of micro-algae and cyanobacteria into bio-based products is increasing but still relatively limited. Past R&I activities related to strain, process and technology developments have brought significant progress for high-value/low-volume specialties based on micro-algae, produced in bioreactors. At the other end of the spectrum, low-value/higher volume products are produced at large scale in open ponds. There is a range of products for which production technologies are available, but not cost competitive. Presently there is a need to upscale production technologies, including downstream separation and purification, which would allow to cover the mid-price range of products in a cost-effective way, thereby contributing to increasing the market penetration of micro-algae derived chemicals and products.\nProposals under this topic should:\n• Demonstrate optimised production, harvesting, and product extraction from micro-algae[4], cyanobacteria and/or other phototrophic bacteria, including aspects related to automation and control when applicable, including a specific focus on downstream separation and purification (quality and purity) of end products depending on final application requirements. Products in scope are those ingredients and intermediates in the medium price range, for which process technologies exist but are currently not cost-competitive enough to meet market demands. The objective is broadening the range of viable products beyond the high-end products for niche markets whose high value presently justifies the use of high-cost technologies.\n• Reduce OPEX and CAPEX with respect to state-of-art, demonstrate the downstream conversion of the produced feedstock into added value products with clear market applications. Cascading and circular use of by-products and side streams is also fully in scope.\n• Ensure that production and conversion of the feedstock are cost-competitive, resources efficient and sustainable (in terms of land use, water use, energy use including RES when it provides added value to the overall business case, nutrients intake, CO2 and effluents). Regarding the optimized production, consider strain selection, optimization, accumulation (intracellular storage) and extraction of desired products, their yield, stability, toxicity, and quality, including purity.\n• Include a task to integrate assessment based on the safe-and-sustainable-by-design (SSbD) framework, developed by the European Commission, for assessing the safety and sustainability of chemicals and materials[5]. Under this context, projects are expected to contribute with and develop recommendations that can advance further the application of the SSbD framework.[6]\nProposals must apply the concept of the ‘multi-actor approach’ and ensure adequate involvement of all key actors in the value chains relevant for this topic, across the sustainable circular bio-based system, including end users and consumers (when targeting B2C products).\nProposals should also describe their contribution to the Specific CBE JU requirements, presented in section 2.2.3.1 of the CBE JU Annual Work Programme 2024[7].\nProposals should seek for links and complementarities and avoid overlaps with past, ongoing and upcoming EU funded projects, including those funded under H2020, HEU and the BBI JU and CBE JU[8], and should ensure a link and synergy with the ‘Restore our Oceans and Waters’ Mission[9] and parallel activities supporting the EU Algae initiative. Collaboration among projects from the same topic are encouraged.\n[1] Updated Bioeconomy Strategy 2018.\n[2] Brussels, 12.05.2021, COM(2021) 400 final.\n[3] COM(2022) 592 final ‘Towards a Strong and Sustainable EU Algae Sector’.\n[4] Phototrophic, heterotrophic and mixed micro-algae strains are in scope\n[5] See document defining the framework and criteria: Safe and sustainable by design.\n[6] More specifically, provide thresholds that can support the criteria definition and improvements for the assessment SSbD methodologies, including any specificities related with bio-based chemicals. Recommendations should also include identification of data gaps, especially safety, environmental, but also socio-economic factors, as well as priorities for data collection.\n[7] https://www.cbe.europa.eu/reference-documents\n[8] Previous BBI JU projects: SpiralG (H2020-BBI-JTI-2017), MULTI-STR3AM (H2020-BBI-JTI-2019), SCALE (H2020-BBI-JTI-2020), MAGNIFICENT (H2020-BBI-JTI-2016), ABACUS (H2020-BBI-JTI-2016), VALUEMAG (H2020-BBI-JTI-2016), REDWine (H2020-BBI-JTI-2020). Previous Horizon2020 projects: SABANA, BIOSEA, ASTRAL, NOM","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-JU-CBE-2024-IA-02"}]}}
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Budget-Based"],"status":"Closed","openingDate":"2021-10-14","deadlineDates":["2022-01-12"],"budget":{"budgetByYear":{"2022":"12000000"},"expectedGrants":2,"minContribution":5000000,"maxContribution":6000000,"deadlineModel":"single-stage"},"keywords":["Transport engineering","Transport engineering, intelligent transport systems"],"description":"Expected Outcome:\nProject results are expected to contribute to all of the following expected outcomes:\n• Concepts, techniques and models based on Artificial Intelligence (AI) used for situational awareness, prediction, decision making and triggering of actions for time critical and safety relevant CCAM applications as well as for cyber threat detection and mitigation.\n• A clear understanding of the capabilities, limitations and potential conflicts of AI based systems for CCAM.\n• Increased user acceptance from an early stage, based on explainable, trustworthy and human-centric AI. Interactions with vehicles using AI should be understandable, human-like and reflect human psychological capabilities, and free of gender, ethnic or other biases.\n• Accelerated AI development and training for CCAM enabled by a relevant set of real and synthetic traffic events and scenarios.\n• AI based CCAM solutions will evolve from reactive and/or adaptive system support into predictive system state awareness (including driver state and user diversity), decision-making and actuation, enhancing road safety especially in near-critical situations.\nScope:\nThe deterministic understanding and consequential design of assistance systems are mostly reactive or to some extent adaptive. In the transition from driver assistance systems towards fully automated systems, a critical aspect is the decision making (i.e. planning and acting), based on robust and reliable detection and perception. AI has a huge potential to advance this process.\nSpecifically, in more complex and dense traffic environments, highly automated driving functions will benefit from the system state prediction enabled by AI. Yet, the current state of technology using AI for CCAM has limitations regarding human-like actions, more specifically the intuitive, split-second (predictive) assessments and ‘reflex decision making’. As such, any AI requires good integration into the overall system with close interaction and compatibility with the active safety systems (e.g. automated emergency braking).\nFor the development process, training is essential for the performance of unbiased AI. It requires sufficient traffic and event data under varying conditions from all over Europe, avoiding limited data sets. The current, mainly deterministic approaches for validation in automotive development will not be sufficient for future training and validation of AI-based or AI-supported functions, which will also need to be able to deal with complex issues as (un)intended miscommunication.\nProposed R&I actions therefore are expected to address all the following aspects\n• Support the development and integration of AI in CCAM with explainable, trustworthy and human-centric and unbiased concepts, techniques and models; this can be on vehicle level and on transport system level, where tactical and strategic links to traffic management and traffic conditions need to be established.\n• Address the knowledge gap on AI training and validation approaches as well as efficient and ethical approaches for data handling of increasing amounts of data.\n• Build upon existing and generated data for training and verification of AI supporting situational awareness in CCAM in more complex traffic scenarios (e.g. digital twins).\nSpecific automotive requirements on functional safety and security need to be considered in the development process of an automotive-grade AI ensuring consistency with existing validation procedures.\nThis topic requires the effective contribution of SSH disciplines and the involvement of SSH experts, institutions, as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.\nIn order to achieve the expected outcomes, international cooperation is advised, in particular with projects or partners from the US, Japan, Canada, South Korea, Singapore, Australia.\nThis topic implements the co-programmed European Partnership on ‘Connected, Cooperative and Automated Mobility’ (CCAM).\nnull\nActivities are expected to achieve TRL 5  by the end of the project – see General Annex B.","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-CL5-2022-D6-01-05"}]}}
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It does not support productive activities, job creation, entrepreneurship, or SME growth as defined by SDG 8.3.\nscope: The project involves international collaboration between the investigator and Prof. Nielsen from UCPH (Denmark), satisfying the scope condition for international participation.","checks":[{"evidence_ids":["s1","s2","s3","s4","s5","s6","s7","s8","s9","s10","s11"],"id":"purpose","missing_evidence":null,"reason":"The project focuses on developing a drug delivery system (emulsions) for therapeutic peptides. 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the absorption site; the intestinal epithelium surface.","start":678,"text_hash":"bf8d53623244447cc926e0a4be41fb82bffc045a6b686328851b21b9a8b65b48"},{"end":1099,"kind":"text","quote":"Simultaneous co-delivery of TPs and PEs is crucial, but not often achieved.","start":1024,"text_hash":"bf8d53623244447cc926e0a4be41fb82bffc045a6b686328851b21b9a8b65b48"},{"end":1374,"kind":"text","quote":"As key deliverables, OraPickering will establish Pickering double emulsions for the encapsulation of hydrophilic TPs and hydrophobic PEs, explore their stability under gastric conditions, and confirm their efficacy and safety for intestinal TP delivery in vitro and in vivo.","start":1100,"text_hash":"bf8d53623244447cc926e0a4be41fb82bffc045a6b686328851b21b9a8b65b48"},{"end":1430,"kind":"text","quote":"To implement OraPickering I will join forces with Prof.","start":1375,"text_hash":"bf8d53623244447cc926e0a4be41fb82bffc045a6b686328851b21b9a8b65b48"},{"end":1591,"kind":"text","quote":"Nielsen from UCPH, 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Peptides","Intestinal Absorption"],"contentUpdateDate":"2023-07-11 16:08:40","topics":[{"code":"HORIZON-MSCA-2022-PF-01-01","title":"MSCA Postdoctoral Fellowships 2022"}],"legalBasis":[{"code":"HORIZON.1.2","title":"Marie Skłodowska-Curie Actions (MSCA)","main":true}],"euroSciVoc":[{"code":"/23/49/315/997","path":"natural sciences/biological sciences/biochemistry/biomolecules","title":"biomolecules"},{"code":"/21/39/179/681","path":"medical and health sciences/clinical medicine/endocrinology/diabetes","title":"diabetes"},{"code":"/21/39/225","path":"medical and health sciences/clinical medicine/oncology","title":"oncology"}],"policyPriorities":{"digitalAgenda":40.0,"cleanAir":40.0,"ai":40.0,"climate":40.0,"biodiversity":0.0},"organisations":[{"name":"KOBENHAVNS UNIVERSITET","shortName":"UCPH","role":"coordinator","country":"DK","city":"KOBENHAVN","activityType":"HES","sme":false,"ecContribution":214934.4,"totalCost":0.0,"geolocation":[55.67452,12.56442],"order":1}],"topicDetails":[{"identifier":"HORIZON-MSCA-2022-PF-01-01","title":"MSCA Postdoctoral Fellowships 2022","callIdentifier":"HORIZON-MSCA-2022-PF-01","callTitle":"MSCA Postdoctoral Fellowships 2022","programme":"Horizon Europe (HORIZON)","programmeDivisions":["Marie Skłodowska-Curie Actions (MSCA)"],"typeOfAction":"HORIZON-TMA-MSCA-PF-EF HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships","typeOfMGA":["HORIZON Unit Grant"],"status":"Closed","openingDate":"2022-05-11","deadlineDates":["2022-09-13"],"budget":null,"keywords":[],"description":"Expected Outcome:\nProject results are expected to contribute to the following outcomes:\nFor supported postdoctoral fellows\n• Increased set of research and transferable skills and competences, leading to improved employability and career prospects of MSCA postdoctoral fellows within academia and beyond;\n• New mind-sets and approaches to R&I work forged through interdisciplinary, inter-sectoral and international experience;\n• Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.\nFor participating organisations\n• Increased alignment of working conditions for researchers in accordance with the principles set out in the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers;\n• Enhanced quality and sustainability of research training and supervision;\n• Increased global attractiveness, visibility and reputation of the participating organisation(s);\n• Stronger R&I capacity and output among participating organisations; better transfer of knowledge;\n• Regular feedback of research results into teaching and education at participating organisations.\nScope:Fellowships will be provided to excellent researchers, undertaking international mobility either to or between EU Member States or Horizon Europe Associated Countries, as well as to non-associated Third Countries. Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.\nPostdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:\n• European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.\n• Global Postdoctoral Fellowships are open to European nationals or long-term residents[1] who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. These fellowships require an outgoing phase of minimum 12 and maximum 24 months in a non-associated Third Country, and a mandatory 12-month return phase to a host organisation based in an EU Member State or a Horizon Europe Associated Country.\nSpecific eligibility conditions apply to MSCA Postdoctoral Fellowships in the research areas covered by the Euratom Research and Training Programme 2021-2025[1].\nSecondments\nResearchers receiving a Postdoctoral Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.\nFor European Postdoctoral Fellowships, secondments cannot exceed one third of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.\nFor Global Postdoctoral Fellowships, optional secondments are permitted for up to one third of the outgoing phase. A maximum of three months can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.\nSecondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.\nPlacements in the non-academic sector\nPostdoctoral Fellowships can provide an additional period of up to six months to support researchers seeking a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country[3]. While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country[4]. The request for such a placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. It must be substantiated by a letter of commitment from the European non-academic organisation where the placement takes place[5]. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.\nIf the placement does not meet the requirements (missing letter of commitment or taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. This might affect the final score.\nTraining activities\nThe training activities implemented under the Postdoctoral Fellowships should include training for key transferable skills[6], foster innovation and entrepreneurship, (e.g. commercialisation of results, Intellectual Property Rights, communication, public engagement and citizen science) and promote Open Science practices (open access to publications and to research data, FAIR data management, etc.).\nCareer Development Plan\nIn order to equip MSCA postdoctoral fellows with skills that enhance and expand their career opportunities inside and outside academia, a Career Development Plan should be established jointly by the supervisor(s) and the researcher. In addition to research objectives, this plan should comprise the researcher's training and career needs, including training on transferable skills, teaching, plannin","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-MSCA-2022-PF-01-01"}]}}
{"id":"101248845","acronym":"PRECISE-TBM","name":"Prospective evaluation and refinement of novel biomarker-based point-of-care tests for the diagnosis of tuberculous meningitis in children","offer":"Childhood Tuberculous meningitis (TBM) is the most severe form of tuberculosis (TB), mostly affecting children. Diagnosis of TBM in children is challenging, necessitating up to six visits to hospitals. Furthermore, 50% of people who are diagnosed with TBM die or suffer life-long neurological problems. We previously identified, patented, and validated a 3-protein cerebrospinal fluid (CSF) biomarker signature, including IFN-γ, for the diagnosis of childhood TBM. We have developed a prototype point-of-care (PoC) lateral flow test based on this biosignature, in collaboration with LifeSADX, an industrial partner based in South Africa. We also developed a variant of the CSF-based test, based on the biosensor technology and have identified blood-based (BB) biomarkers which require refinement and subsequent development into a TBM PoC test. The potential alterations of IFN-γ detection or function due to autoantibodies or genetic mutations in these patients is currently unknown. In this project, we aim to:1) Gather evidence on the performances of the two newly developed CSF-based PoC tests at hospitals situated in South Africa, Zambia, and Zimbabwe2) Refine our previously identified BB-biosignature in stored multi-country specimens, and incorporate the refined biomarkers into a new TBM prototype test, using biosensor technology3) Prospectively evaluate the blood-based prototype test alongside the CSF-based tests4) Test both immunologically and genetically, defects in IFN-γ immunity, a key biomarker on our CSF-based tests, in CSF and serum samples, and ascertain the relevance of such defects to possible disease development, and their influence on PoC test resultsThe project will bring together a multi-disciplinary team with different but complementary expertise including immunologists, human geneticists, neurologists, social scientists, and an industrial partner based in South Africa, and has potential to significantly influence the management of childhood TBM worldwide.","objective":"Childhood Tuberculous meningitis (TBM) is the most severe form of tuberculosis (TB), mostly affecting children. Diagnosis of TBM in children is challenging, necessitating up to six visits to hospitals. Furthermore, 50% of people who are diagnosed with TBM die or suffer life-long neurological problems. We previously identified, patented, and validated a 3-protein cerebrospinal fluid (CSF) biomarker signature, including IFN-γ, for the diagnosis of childhood TBM. We have developed a prototype point-of-care (PoC) lateral flow test based on this biosignature, in collaboration with LifeSADX, an industrial partner based in South Africa. We also developed a variant of the CSF-based test, based on the biosensor technology and have identified blood-based (BB) biomarkers which require refinement and subsequent development into a TBM PoC test. The potential alterations of IFN-γ detection or function due to autoantibodies or genetic mutations in these patients is currently unknown. In this project, we aim to:1) Gather evidence on the performances of the two newly developed CSF-based PoC tests at hospitals situated in South Africa, Zambia, and Zimbabwe2) Refine our previously identified BB-biosignature in stored multi-country specimens, and incorporate the refined biomarkers into a new TBM prototype test, using biosensor technology3) Prospectively evaluate the blood-based prototype test alongside the CSF-based tests4) Test both immunologically and genetically, defects in IFN-γ immunity, a key biomarker on our CSF-based tests, in CSF and serum samples, and ascertain the relevance of such defects to possible disease development, and their influence on PoC test resultsThe project will bring together a multi-disciplinary team with different but complementary expertise including immunologists, human geneticists, neurologists, social scientists, and an industrial partner based in South Africa, and has potential to significantly influence the management of childhood TBM worldwide.","sourceVersion":"e086e9f5a30c26948ec500ce018ddcef24a359877fb36d002707d7ba475bf300","originalSourceVersion":"ce5ea70aeb4aff26225cacd4d99e08e660f95914dffa742bae03216ab4d9e762","textHash":"a946a4cf041f2c6a034a38b5202cdd62d93d2386744570064bb2bb992902c68e","sourceUrl":"https://cordis.europa.eu/project/id/101248845","country":"ZA","participantCountries":["DE","FR","ZA","ZM","ZW"],"programme":"HORIZON","status":"SIGNED","sourceUpdated":"2026-05-20 12:42:58","locations":[],"goal":3,"goalIds":[3,9],"rels":[{"code":"3","name":"Ensure healthy lives and promote well-being for all at all ages","uri":"http://data.europa.eu/sdg/3","state":"supported","strength":"strong","assertionId":"mapping:81c564b01377d5eaa04001cdc7f461cd573a6e246d78a40bc13bbb723f69b119","revision":1,"reviewStatus":"unreviewed","claim":"Project source excerpt (planned): “In this project, we aim to:1) Gather evidence on the performances of the two newly developed CSF-based PoC tests at hospitals situated in South Africa, Zambia, and Zimbabwe2) Refine our previously identified BB-biosignature in stored multi-country specimens, and incorporate the refined biomarkers into a new TBM prototype test, using biosensor technology3) Prospectively evaluate the blood-based prototype test alongside the CSF-based tests4) Test both immunologically and genetically, defects in IFN-γ immunity, a key biomarker on our CSF-based tests, in CSF and serum samples, and ascertain the relevance of such defects to possible disease development, and their influence on PoC test resultsThe project will bring together a multi-disciplinary team with different but complementary expertise including immunologists, human geneticists, neurologists, social scientists, and an industrial partner based in South Africa, and has potential to significantly influence the management of childhood TBM worldwide.”","modality":"planned","hypothesis":null,"quote":"In this project, we aim to:1) Gather evidence on the performances of the two newly 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Proposals under this topic should aim to deliver results that are contributing to at least one of the following expected outcomes:\n• Generate beyond proof of concept data with innovative ideas or inventions that will improve the uptake, adherence or implementation of preventative/treatment/diagnostic solutions;\n• Progress an innovative approach that makes products and services (more) accessible and affordable to commercially unattractive markets or serves vulnerable populations in SSA;\n• Progress an innovative approach that addresses community-driven and trusted demand for new or repurposed tools, including those needed by hard-to-reach communities;\n• Deliver innovative technologies which can generate accelerated cross-disease solutions, including communicable disease specific solutions;\n• Repurpose or extend the use of an existing preventative/treatment/diagnostic intervention.\n[1] Disruptive Technologies: Catching the Wave (hbr.org)\nScope:Scope\nThe objective of the topic is to progress a development which meet at least one of the below:\n• Innovations in R&D or products implementation focusing on new or improvement of existing medicinal products and delivery systems of new or improved medical technologies within the health systems. This may include but not limited to use of new technologies;\n• Development of a new intervention or improvements of an existing intervention for age-appropriate formulations or underserved populations. This may include but not limited to development of paediatric or geriatric formulations generating data for patients with co-morbidities;\n• Development of tools to improve the affordability or accessibility of preventative/ treatment/ diagnostic solutions in SSA or specific vulnerable populations as relevant. This may include but not limited to development of thermostable or humid resistant formulations, lower cost of goods, dose sparing approaches;\n• Accelerate the development of delivery systems which will improve the efficacy or uptake of the preventative/treatment/diagnostic solutions in SSA. This may include but not limited to assessing different route of administration ensuring easier access, new or improved devices or equipment ensuring higher efficacy or uptake, etc;\n• Leverage existing data to repurpose and expand the use of the preventative/ treatment/ diagnostic intervention. This may include but not limited to using well-established safety and pharmacological data from its use in one disease area into the infectious disease field in the scope of the Global Health EDCTP3.\nScope includes infectious diseases in scope of the Global Health EDCTP3 including HIV/AIDS. Proposalsare to generate beyond proof-of-concept data.\nOut of scope: infectious diseases not in scope of the Global Health EDCTP3, potential solutions tacklingchronic diseases potentially caused by infections, and non-communicable diseases.\nApplicants are invited to address the following in the proposals:\n• Proposals should clearly define the challenge or unmet need they are addressing. 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2023","programme":"Horizon Europe (HORIZON)","programmeDivisions":["Global Challenges and European Industrial Competitiveness","Civil Security for Society","Protection and Security"],"typeOfAction":"HORIZON-IA HORIZON Innovation Actions","typeOfMGA":["HORIZON Action Grant Budget-Based"],"status":"Closed","openingDate":"2023-06-29","deadlineDates":["2023-11-23"],"budget":{"budgetByYear":{"2023":"7000000"},"expectedGrants":1,"minContribution":7000000,"maxContribution":7000000,"deadlineModel":"single-stage"},"keywords":["Big data","Data protection","Data protection and privacy","Design, implementation, and operation of data management systems that include security and privacy functions","Education and training of police authorities","Fight against crime and terrorism","Information management","Police authorities"],"description":"Expected Outcome:\nProjects’ results are expected to contribute to all of the following outcomes:\n• Improved capabilities of European Police Authorities and other relevant security practitioners for a fast and flexible analysis of huge amounts of heterogeneous data through the application of robust and advanced tools, allowing them to efficiently fight criminals and terrorists who use novel technologies;\n• Enhanced and modern analysis of heterogeneous data as well as training curricula that take into account legal and ethical rules of operation, cost-benefit considerations, as well as fundamental rights such as privacy and protection of personal data, providing reports that can be used in court;\n• The work of European Police Authorities in the area of fighting crime and terrorism is supported by big data analysis that is in accordance with data minimisation principles and high privacy standards, with clearly identified challenges, adequate models and scientifically validated technical options for tackling the challenge proposed and solutions developed that meet the challenge.\nScope:\nWith the constant increase of technological developments, the processing of large datasets is inevitable for police work in today’s digital world. As a wide range of products and services become digitalised and interconnected, Police Authorities need adequate technologies to properly detect and counter emerging threats. Big data analysis also provides invaluable opportunities to carry out investigations, identify suspects, reveal or anticipate crime patterns or links between previously unconnected events or actors. In particular, there is a continuous need for handling large, complex and unstructured datasets, in order to gather, normalise, process, connect, prioritise, visualise the data (including text, image, audio and video) in ways that facilitate the extraction of actionable intelligence, while ensuring interoperability between existing systems and standards in different Member States. Solutions to perform temporal and geospatial analyses are needed too. The successful proposal should have a clear strategy related to quality data sets to be used for training and testing. The innovation efforts should provide support to web-based data analysis that can facilitate e.g. the fight against hate speech, human trafficking, terrorism or child sexual exploitation in an online environment. The work should include surface, deep and dark web.\nExamples of relevant techniques include: examination of digitally captured signatures, identification of voice cloning and of deepfakes; detection and recognition of persons/objects/logos; speaker diarisation and identification; speech recognition and transcription into text; automatic classification of text based on risk factors; optical character recognition; named entity recognition; concept extraction, extraction of entities and relations between them in unstructured text; multimodal analytics, in order to discover insights and patterns in large volumes of data through clustering, as well as the identification of user communities and key actors in the social networks being formed online; automatic correlations among all available sources, as well as cross-checking, cross-matching and mapping information between different cases, i.e. cross-reference with existing records in databases of Police Authorities. Identification of perpetrators can also be enhanced by detecting their online behaviour and habits, e.g. which days/hours they are used to login/logout.\nTaking advantage of these modern technologies will require Police Authorities to move away from business models based on data input to data evaluation. It will require robust and reliable information management structures that encompass all aspects from data collection to handling, evaluation, exploitation and data security. In particular, key principles such as lawfulness of processing and data minimisation should apply to ensure that Police Authorities conduct data analysis in full compliance with fundamental rights and EU privacy and personal data protection legal framework. For example, it may be necessary to filter and reduce large datasets to what is relevant for operational support activities and in investigations, and/or apply methods such as differential privacy. Hence, all these efforts should also reconcile big data analysis and data protection, i.e.: explore challenges to conduct big data analysis in accordance with data minimisation principles and data protection by default standards, propose possible models and scientific options to tackle the challenge, and develop solutions (digital tools) that meet the challenge, focusing on triage and clustering functions. Possibilities of assessing and preventing bias and discrimination as a result of big data analysis should be analysed too. The successful proposal should thus help framing the issue of big data analysis for Police Authorities, providing guidelines as well as operational tools to comply with EU data protection law.\nThe successful proposal should build on the publicly available achievements and findings of related previous national or EU-funded projects as well as create synergies with similar on-going security research projects from the Calls 2021-2022 on Fighting Crime and Terrorism in the area of modern information analysis, in order to avoid duplication and to exploit complementarities as well as opportunities for increased impact.\nIn this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.\nProposals funded under this topic are expected to engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community.\nPossibilities of coordination with related activities funded through t","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-CL3-2023-FCT-01-01"}]}}
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The project will reassess and analyse the results of its unpublished excavations, examining the surrounding agricultural and rural landscape through new Historical Landscape Characterization (HLC) analyses and archaeological surveys in an adjacent unurbanised area. This will help collect data to map the site’s social history. REFUGE is one of the first projects to apply HLC in Cyprus. By reconstructing the social history of the AAB community, the project aims to trace its economic networks and understand its role within broader regional dynamics across the Mediterranean and the Levant. It will also investigate interactions and mutual contributions among various cultures and groups, including the analysis of specific samples of amphorae and tableware from the site, materials that remain largely unexplored. REFUGE employs an integrated, cross-disciplinary approach, combining archival research, architectural analysis, excavation data, material culture studies, and topographical reconstruction. The findings from this project will contribute to scholarly publications and be made accessible to the public through free multimedia resources, featuring multilingual voice narration to ensure broad accessibility.","objective":"REFUGE – Religious Enclosures in Fortified Urban and Rural Geographies of the Eastern Mediterranean aims to provide a new interpretation of Late Antique fortified churches. The project will explore whether these structures can be seen as safe spaces and gathering loci for communities, as well as centres for a culture under threat. 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By reconstructing the social history of the AAB community, the project aims to trace its economic networks and understand its role within broader regional dynamics across the Mediterranean and the Levant. It will also investigate interactions and mutual contributions among various cultures and groups, including the analysis of specific samples of amphorae and tableware from the site, materials that remain largely unexplored. REFUGE employs an integrated, cross-disciplinary approach, combining archival research, architectural analysis, excavation data, material culture studies, and topographical reconstruction. 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Through ERA4You, as one of the ERA Policy Actions[1], the European Commission aims to support and incentivise such transformations, towards a more balanced circulation of talents, both trans-nationally and across sectors. Within this scope, ERA Talents aims to support training and mobility of researchers, innovators, and other research and innovation talents across sectors with a particular focus on widening countries. The grant covers expenses related to the ERA Talents participating organisations and individual talents hosted/seconded (administrative costs, training costs, travel and subsistence costs and salaries for seconded staff, and costs associated with dissemination & communication and transfer of knowledge).\nExperimentation. Complementary to ERA Chairs, Excellence Hubs, ERA Fellowships and MSCA Staff Exchanges, the ERA Talents scheme promotes innovative inter-sectoral collaboration in research and innovation through cross-sectoral exchange of staff, with a focus on widening countries. This call particularly encourages experimentation by diverse and heterogeneous consortia in order to develop best practices for intersectoral talent circulation at the benefit of widening countries. Grants awarded under this topic will be invited to collaborate with each other and participate in mutual learning exercises.\nIntersectoral mobility. Actions are invited to develop activities in view of realising one or more of the following European Commission’s objectives regarding intersectoral mobility. The European Commission aims at selecting a portfolio of complementary actions where possible.\n• Strengthening academia/non-academia cooperation, and reinforcing innovation ecosystems, focussing on establishment of public-private links, private sector involvement booster, activities for the transfer of researcher know-how to businesses, as well as activities that foster closer involvement of business sector staff in training of academic staff.\n• Improving training and lifelong learning for researchers, innovators, and other research and innovation talents, characterised by opportunities for upskilling and interdisciplinary skill development. In particular, (i) training for specific in-demand skills by industry or other non-academic sectors in specific thematic areas, such as Missions and Partnerships, greening of society, to improve employability and interoperability, and (ii) training to build R&I support capacity (‘other research and innovation talents’), such as knowledge brokers, data stewards, research managers, research infrastructure operators, knowledge and technology transfer officers, etc.\n• Boosting researcher entrepreneurship, focused on development of entrepreneurial skills (e.g. business economics, business creation, knowledge transfer, intellectual property rights and other relevant legal framework) for researchers and commercialisation or other valorisation training and support for researchers, through preparatory activities for entrepreneurship and support for researcher start-up creation.\nParticipating organisations. 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The joint training and mobility methodology presented by the applicant consortium should include an approach to identify a diverse audience of research and innovation talents engaging in the action, outlined in the application. The ERA talent should have a secondment term within one (or more) of the participating organisations. Supported staff members must be actively engaged in or linked to R&I activities or R&I support activities for at least 6 months (full-time equivalent) at the sending institution before the first period of secondment.\nProposers are requested to provide an estimate of the number of ‘ERA talents’ the action is going to provide with a mobility opportunity. Secondments are open to researchers, innovators, and other research and innovation talents – such as administrative, managerial and technical staff supporting R&I activities in their organisations – from any career stage, excluding though doctoral candidates (PhD students). 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Regular feedback of research results into teaching and education at participating organisations.\nScope:\nFellowships will be provided to excellent researchers undertaking international mobility. Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.\nPostdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:\n• European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.\n• Global Postdoctoral Fellowships are open to European nationals or long-term residents[1] who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. These fellowships require an outgoing phase of minimum 12 and maximum 24 months in a non-associated Third Country, and a mandatory 12-month return phase to a host organisation based in an EU Member State or a Horizon Europe Associated Country.\nSpecific eligibility conditions apply to MSCA Postdoctoral Fellowships in the research areas covered by the Euratom Research and Training Programme 2021-2025[1].\nSecondments\nResearchers receiving a Postdoctoral Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.\nFor European Postdoctoral Fellowships, secondments cannot exceed one third of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.\nFor Global Postdoctoral Fellowships, optional secondments are permitted for up to one third of the outgoing phase. A maximum of three months of such secondments can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.\nSecondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.\nPlacements in the non-academic sector\nPostdoctoral Fellowships can provide an additional period of up to six months to support researchers opting for a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country[3]. While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country[4]. The request for such a non-academic placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.\nIf the placement does not meet the requirements (taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. This might affect the final score.\nTraining activities\nThe training activities implemented under the Postdoctoral Fellowships should include training for key transferable skills, foster innovation and entrepreneurship, (e.g. commercialisation of results, Intellectual Property Rights, communication, public engagement and citizen science), foster good scientific conduct such as research integrity and promote Open Science practices (open access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science etc.).\nCareer Development Plan\nIn order to equip MSCA postdoctoral fellows with skills that enhance and expand their career opportunities inside and outside academia, a Career Development Plan should be established jointly by the supervisor(s) and the researcher. 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{"id":"101204252","acronym":"GESTICO","name":"From hands to concepts: evolutionary and developmental origins of gesture iconicity","offer":"The GESTICO project will explore the developmental and evolutionary origins of gestural iconicity, by examining the spatial properties of gestures that convey meaning independently of semantic communication. The relevance of different amplitudes and lateralisation of gestures in reference to spatio-numerical and/or emotional magnitudes will be tested in non-human primates (Chimpanzees, Bonobos, Guinea baboons, and Barbary macaques) and preverbal human infants. Observational data from chimpanzees and bonobos will be used to investigate whether the amplitude and laterality of their communicative gestures are meaningful, by testing their correlation with specific social or emotional contexts, and whether they impact the responses of recipients (WP1). Movement analyses, based on newly developed deep learning tools, will be used to enable quantitative measures on gestures. Once the methodology of gesture spatialisation description is established for great apes, similar analyses will be applied to gestures of captive Guinea baboons and Barbary macaques (WP2). Finally, a habituation paradigm measuring looking times will assess the ability of human infants aged 10 to 12 months to spontaneously associate concepts of magnitude (quantities) with metaphorical manual gestures differing in their spatial amplitude (WP3).Collaboration between the host organisation, the Wild Minds Lab (University of St Andrews), the Eco-Anthropology Lab (French National Museum of Natural History), and the Integrative Neuroscience and Cognition Center (Paris Cité University) will facilitate an interdisciplinary approach, enabling cross-species comparisons around common concepts. The complementary use of innovative observational and experimental approaches will contribute to a better understanding of the emergence of the form-function link in the gestural communication of catarrhine primates (Afro-Eurasian species, including humans), and the associated cognitive mechanisms.","objective":"The GESTICO project will explore the developmental and evolutionary origins of gestural iconicity, by examining the spatial properties of gestures that convey meaning independently of semantic communication. The relevance of different amplitudes and lateralisation of gestures in reference to spatio-numerical and/or emotional magnitudes will be tested in non-human primates (Chimpanzees, Bonobos, Guinea baboons, and Barbary macaques) and preverbal human infants. Observational data from chimpanzees and bonobos will be used to investigate whether the amplitude and laterality of their communicative gestures are meaningful, by testing their correlation with specific social or emotional contexts, and whether they impact the responses of recipients (WP1). Movement analyses, based on newly developed deep learning tools, will be used to enable quantitative measures on gestures. Once the methodology of gesture spatialisation description is established for great apes, similar analyses will be applied to gestures of captive Guinea baboons and Barbary macaques (WP2). Finally, a habituation paradigm measuring looking times will assess the ability of human infants aged 10 to 12 months to spontaneously associate concepts of magnitude (quantities) with metaphorical manual gestures differing in their spatial amplitude (WP3).Collaboration between the host organisation, the Wild Minds Lab (University of St Andrews), the Eco-Anthropology Lab (French National Museum of Natural History), and the Integrative Neuroscience and Cognition Center (Paris Cité University) will facilitate an interdisciplinary approach, enabling cross-species comparisons around common concepts. 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These emissions are more than any EU state and if the sector was a country, it would rank as the sixth highest in the world. In 2015, shipping accounted for 13% of overall EU greenhouse gas emissions from the transport sector[1]. Overwhelmingly, long distance shipping accounts for the majority of GHG emissions and its decarbonisation is particularly challenging. It is expected that solutions will need to combine a variety of technologies, operational practices, energy sources and efficiency measures. Furthermore, it will be essential to link any measures to robust data and measurements to better quantify their effectiveness and optimisations.\nScope:All following aspects should be addressed:\n• Working together with, for example operators, ship builders, marine equipment manufacturers, fuel and energy suppliers and others research will address the development of technologies combined with operational practices to substantially reduce GHG emissions from long distance shipping in line with the IMO target and without increasing other forms of pollution.\n• Excluding fuel development, a wide range of potential solutions can be proposed including the use of wind and solar assistance combined with efficiency improvements and other alternate energies. Solutions can be proposed in combination and should take into account the likely availability of infrastructure (including bunkering) on long distance routes.\n• Solutions should also take into account the CO2 equivalent from any reduction of black carbon emissions.\n• Costs, GHG reductions and any other potential waste streams shall be convincingly analysed using real data and testing programmes in addition to theoretical analysis.\n• Implications for the provision of new infrastructures shall be quantified and assessed.\n• To at least TRL5, technologies, systems and practices shall be tested at full scale on operational shipping. The differences between predicted and measured data should be identified.\n• Any reduction in GHG emissions that are founded upon innovative operational practices must be robustly benchmarked against the current state of the art, for example concerning ship routings and speeds through the use of “big” AIS “data“ and/or other satellite data.\n• A robust communication strategy should be developed and implemented so as to ensure wider public engagement as well as a strong engagement with the global shipping sector and its customers.\n• Cooperation with IMO and EU activities and fora concerning the decarbonisation of shipping is encouraged. Build upon and cooperate with any related activities and research.\nThe Commission considers that proposals requesting a contribution from the EU of between EUR 5 to 10 million would allow the specific challenge to be addressed appropriately.\nExpected Impact:Development of innovative solutions to decarbonise shipping that exceed the IMO’s 2050 target to decarbonise by 50% and which are applicable to ship types that are the largest emitters of GHGs such as: bulk carriers, tankers, container ships, cruise ships and passenger liners. Establishment of robust benchmarks and methods which will provide wide confidence of the “real world” impacts from any specific GHG reduction measure including potential scalability and any secondary environmental impacts. Improve the competitiveness of European maritime industries and shipping companies within the field of green shipping. Increase the awareness and take up by end users. Provide evidence to policy makers within EU and globally concerning infrastructure requirements necessary to meet the 2050 decarbonisations target.\nCross-cutting Priorities:Blue Growth\n[1]https://www.eea.europa.eu/data-and-maps/indicators/transport-emissions-of-greenhouse-gases/transport-emissions-of-greenhouse-gases-10.","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/LC-MG-1-13-2020"}]}}
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Accordingly, there is a growing demand for microfluidic systems that support long-term cell growth in well-controlled conditions and allow reproducible and sequential multi-step operations in an automated fashion. This project is aiming to fulfill these needs through the development of an integrated microfluidic device consisting of multiple individual bioreactors, which will allow single-cell entrapment, cultivation, monitoring and analysis under strictly controlled conditions and long periods of time. By utilizing the developed system with genetically identical yeast cells we will investigate how epigenetic and genetic factors interact to enhance the adaptation process and how the adapted state is maintained in populations. The multidisciplinary approach of this project will make it possible to tackle these and other questions in a quantitative and systematic way. 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However, despite these exciting promises, the vast majority of cell-based microfluidic devices available today are still in the proof-of-concept state. Accordingly, there is a growing demand for microfluidic systems that support long-term cell growth in well-controlled conditions and allow reproducible and sequential multi-step operations in an automated fashion. This project is aiming to fulfill these needs through the development of an integrated microfluidic device consisting of multiple individual bioreactors, which will allow single-cell entrapment, cultivation, monitoring and analysis under strictly controlled conditions and long periods of time. By utilizing the developed system with genetically identical yeast cells we will investigate how epigenetic and genetic factors interact to enhance the adaptation process and how the adapted state is maintained in populations. 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Focus will be on companies proposing disruptive ICT concepts, products and services applying new sets of rules, values and models which ultimately create new markets (e.g. by tackling non consumption) or disrupt existing markets.\nThe objective of the ODI is threefold:\n1. Nurture promising innovative and disruptive ideas;\n2. Support their prototyping, validation and demonstration in real world conditions;\n3. Help for wider deployment or market uptake.\nProposed projects should have a potential for disruptive innovation and fast market up-take. In particular it will be interesting for entrepreneurs and young innovative SMEs, including start-ups that are looking for swift support to their innovative ideas.\nScope:The SME instrument consists of three phases, including a coaching and mentoring service for beneficiaries. Participants can apply to phase 1 or directly to phase 2.\nIn phase 1, a feasibility study shall be developed in order to verify the technological/practical as well as economic viability of an innovation idea/concept with considerable novelty to the industry sector in which it is presented (new products, processes, design, services and technologies or new market applications of existing technologies). The activities could, for example, comprise risk assessment, market study, user involvement, Intellectual Property (IP) management[1],\ninnovation strategy development, partner search, feasibility of concept and the like to establish a solid high-potential innovation project aligned to the enterprise strategy and with a European dimension. Bottlenecks in the ability to increase profitability of the enterprise through innovation shall be detected and analysed during phase 1 and addressed during phase 2 to increase the return in investment in innovation activities. The proposal should contain an initial business plan based on the proposed idea/concept. It should outline the specifications of a more elaborate business plan, which is to be the outcome of the project, and the criteria for success.\nFunding will be provided in the form of a lump sum of EUR 50.000. Projects should last around 6 months.\nIn phase 2, innovation projects[2]\nwill be supported that address the specific challenges identified and that demonstrate high potential in terms of company competitiveness and growth underpinned by a strategic business plan. Activities should focus on innovation activities such as demonstration, testing, prototyping, piloting, scaling-up, miniaturisation, design, market replication and the like aiming to bring an innovation idea (product, process, service etc.) to industrial readiness and maturity for market introduction, but may also include some research. For technological innovation, Technology Readiness Levels of 6 or above (or similar for non-technological innovations) are envisaged; please see part G of the General Annexes.\nProposals shall be based on an elaborate business plan. Particular attention must be paid to IP protection and ownership; applicants will have to present convincing measures to ensure the possibility of commercial exploitation ('freedom to operate').\nProposals shall contain a specification for the outcome of the project and criteria for success. They will include an explanation of how the results of the supported project are to be commercialised and of what kind of impact on the company is expected.\nThe Commission considers that proposals requesting a contribution from the EU of between EUR 0.5 and 2.5 million[3]\nwould allow phase 2 to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts (higher or lower). Projects should last between 12 and 24 months. [4]\nPhase 3 of the SME Instrument aims to increase the economic impact of the funding provided by the SME Instrument phase 1&2 grants and by the business coaching. Phase 3 is not subsequent to phase 1 and/or 2, but provides specific support to SME instrument beneficiaries during and after phase 1 or 2.\nAll support under phase 3 of the SME instrument will be accessible through a single, dedicated entry point, which will serve as an information portal and a networking space.\nThis platform will offer access to two main strands of services:\n• Access to markets\n• Access to finance\nIn addition, phase 3 will create opportunities for partnering, networking and training, which are set out in the Dedicated Support Actions at the end of this call.\nSME Instrument beneficiaries are also offered dedicated business innovation coaching and mentoring support. This service is facilitated by the Enterprise Europe Network and delivered by a dedicated coach through consultation and signposting to the beneficiaries. The coaches are recruited from a central database managed by the Commission and have all fulfilled stringent criteria with regards to business experience and competencies.\nThroughout the three phases of the instrument, the Network will complement the coaching support by providing access to its innovation and internationalisation service offering. This could include, for example, depending on the need of the SME, support in identifying growth potential, developing a growth plan and maximising it through internationalisation; strengthening the leadership and management skills of individuals in the senior management team and developing in-house coaching capacity; developing a marketing strategy or raising external finance.\nExpected Impact:  • Enhancing profitability and growth performance of SMEs by combining and transferring new and existing knowledge into innovative, disruptive and competitive solutions seizing European and global business opportunities.\n• Market uptake and distribution of innovations[5]  tackling the specific challenges in a sustainable way.\n• Increase of private investment in innovation, notably leverage of pr","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/SMEInst-01-2016-2017"}]}}
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Latvian universities barely reach international standards in strategic areas such as the foundation and last-generation ICT science and technology like Artificial Intelligence, Data Science, and Dynamic Systems Modeling. In these sectors, Latvia is lagging behind compared to other European countries and aims at bridging  the knowledge gap.To achieve the objectives, a research component of the work plan aims at targeting universities, incubators, research centers, NCPs.  An intertwined set of  Communication and Support activities aim at reaching the broadest community of junior and senior researchers,  Twinning project’s teams and other EC initiatives, Latvian policy and decision makers. A common  research agenda will address scientific challenges related to the use of  satellite data for environmental applications, as accompanying  measures,  computational infrastructure upgrades, doctoral schools, workshops, exchange visits and seminars will be implemented.The outcomes will be critically important to  increase the ability and capacity of Latvian universities to carry out large-scale and high-quality research in the aforementioned domains.  Capacity building will result in the  emergence of Latvian universities' excellence for proactively cooperating in EU research programmes over the coming decade.","objective":"TED4LAT is a Coordination and Support Action proposal targeting the overarching objective of the call HORIZON-WIDERA-2021-ACCESS-03-01: Twinning to reach high international standards in research and innovation in Latvia.  It will be implemented by twinning two prominent research institutions in France, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, and in Italy, Politecnico di Torino, with  three widening Latvian Universities (Liepaja University, Vidzeme University of Applied Sciences, and Riga Technical University). The Baltic Open Solutions Center, a Latvian SME, joins the endeavor  as a living-lab application partner. Latvian universities barely reach international standards in strategic areas such as the foundation and last-generation ICT science and technology like Artificial Intelligence, Data Science, and Dynamic Systems Modeling. In these sectors, Latvia is lagging behind compared to other European countries and aims at bridging  the knowledge gap.To achieve the objectives, a research component of the work plan aims at targeting universities, incubators, research centers, NCPs.  An intertwined set of  Communication and Support activities aim at reaching the broadest community of junior and senior researchers,  Twinning project’s teams and other EC initiatives, Latvian policy and decision makers. A common  research agenda will address scientific challenges related to the use of  satellite data for environmental applications, as accompanying  measures,  computational infrastructure upgrades, doctoral schools, workshops, exchange visits and seminars will be implemented.The outcomes will be critically important to  increase the ability and capacity of Latvian universities to carry out large-scale and high-quality research in the aforementioned domains.  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Twinning actions intend to help raise the research profile of the institution from the Widening country as well as the research profile of its staff including a special focus on strengthening the research management and administrative skills of the coordination institution from the Widening country.\nProject results are expected to contribute to all of the following expected outcomes:\n• Improved excellence capacity and resources in Widening countries enabling to close the still apparent research and innovation gap within Europe.\n• Enhanced strategic networking activities between the research institutions of the Widening countries and at least two internationally-leading counterparts at EU level.\n• Raised reputation, research profile and attractiveness of the coordinating institution from the Widening country and the research profile of its staff.\n• Strengthened research management capacities and administrative skills of the staff working in institutions from the Widening country.\n• Improved creativity supported by development of new approaches in R&I collaboration, increased mobility (inwards and outwards) of qualified scientists.\nScope:Twinning proposals should have to clearly outline the scientific strategy for stepping up and stimulating scientific excellence and innovation capacity in a defined area of research as well as the scientific quality of the partners involved in the twinning exercise. This scientific strategy should include arrangements for formulating new (or ongoing) joint research project(s) in the scientific area of choice and describe how Twinning will take this research to a new stage, by enlarging its scope and/or the research partnership. If relevant, any links with sustainable development objectives are to be outlined.\nSuch a strategy should include a comprehensive set of activities to be supported. These should include at least a number of the following: short-term staff exchanges; expert visits and short term on-site or virtual training; workshops; conference attendance; organisation of joint summer school type activities; dissemination and outreach activities. As far as appropriate these activities should take into account the gender equality plans of the participants.\nProposals should also focus on strengthening the research management and administration skills of the coordinating institution from the Widening country. This should take the form of a dedicated work package or task, placing emphasis to specific activities, in view of helping the staff of the coordinating institution to improve their proposal preparation and project management/administration skills. If not yet in place, setting up/upgrading a research management/administration unit within the coordinating institution would be beneficial. This will be achieved by fully utilising the experience and best practices of the internationally leading partners and is expected to be a concrete deliverable of the Twinning exercise.\nA research component not exceeding 30% of the total Horizon Europe grant may include an exploratory research project. This will open opportunities for integrating smaller research activities and by this strengthening the commitment and the engagement of the twinning partners.\nThe Twinning proposals should illustrate quantitatively and qualitatively the expected potential impact of the twinning exercise within the coordinating institution (and possibly at regional/national level) based on indicators such as expected future publications in peer reviewed journals, collaboration agreements with businesses, intellectual property, new innovative products or services, number of international students, number of women scientists and their roles in the research institutions.\nIt should be explained how the leading scientific institutions in the partnership will contribute in terms of provision of access to new research avenues, creativity and the development of new approaches, as well as acting as a source for increased mobility (inwards and outwards) of qualified scientists and young researchers including doctoral candidates. The benefits for the leading scientific institutions and the way they would materialise through the partnership should be substantiated.\nSpecific attention should be paid to gender equality objectives, in line with the organisations’ commitments through their adopted gender equality plans, and in line with ERA objectives, as far as appropriate.\nThe research part of the project should be presented through a dedicated work package and plan including the scientific objectives, tasks and roles of the partners.\nThe duration of the Twinning project should be up to 3 years.","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-WIDERA-2021-ACCESS-03-01"}]}}
{"id":"763805","acronym":"InnoITeam","name":"Centre of Excellence in IT Science and Technology","offer":"To address and promote growth in several technological sectors in Lithuania and encourage EU teaming in ICT-related research and innovation, the overall objective of the project is to create a new Centre of Excellence (CoE) in IT Science and Technology for the Internet of Things and Smart Living Systems, which will be referred to as “InnoITeam”. The long-term vision for InnoITeam is to:● Become the leading provider of innovative technologies for IoT and Big Data for the improvement of the growing technological personal and industry needs in Europe;● Consolidate research and development, education and training, and networking and promotion resources activities in Information and Communications Technology (ICT); ● Coordinate, integrate and support research excellence and innovation development in Lithuania, the Baltic Sea region, and Europe;● Support researchers, academics, industry partners and entrepreneurs in the field of ICT, particularly in IoT, to produce innovations beneficial for the society and economy of Lithuania and beyond.To achieve this long-term vision, the CoE will leverage the knowledge, experience and resources of three Lithuanian institutions – KTU, VGTU and SECR- with the support of two advanced EU partners from Sweden – LiU and TII – in four strategic research and innovation (R&D) topics: R&D Topic 1: User interfacing and interaction design approaches for Smart Environments based on IoT;R&D Topic 2: Cybersecurity aspects in the Smart Environments based on IoT;R&D Topic 3: Data analysis and visualization approaches for data intensive IoT environments;R&D Topic 4: Cognitive IoT technologies for Smart Home Environments.This project has the full support of the Lithuanian Government because it fits perfectly with several of the national priorities within the SMART Specialisation Strategy approved by the Government, and, will allow an enhanced usage and further growth of the recently upgraded infrastructure for ICT research in Lithuania.","objective":"To address and promote growth in several technological sectors in Lithuania and encourage EU teaming in ICT-related research and innovation, the overall objective of the project is to create a new Centre of Excellence (CoE) in IT Science and Technology for the Internet of Things and Smart Living Systems, which will be referred to as “InnoITeam”. 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● Coordinate, integrate and support research excellence and innovation development in Lithuania, the Baltic Sea region, and Europe;● Support researchers, academics, industry partners and entrepreneurs in the field of ICT, particularly in IoT, to produce innovations beneficial for the society and economy of Lithuania and beyond.To achieve this long-term vision, the CoE will leverage the knowledge, experience and resources of three Lithuanian institutions – KTU, VGTU and SECR- with the support of two advanced EU partners from Sweden – LiU and TII – in four strategic research and innovation (R&D) topics: R&D Topic 1: User interfacing and interaction design approaches for Smart Environments based on IoT;R&D Topic 2: Cybersecurity aspects in the Smart Environments based on IoT;R&D Topic 3: Data analysis and visualization approaches for data intensive IoT environments;R&D Topic 4: Cognitive IoT technologies for Smart Home Environments.This project has the full support of the Lithuanian Government because it fits perfectly with several of the national priorities within the SMART Specialisation Strategy approved by the Government, and, will allow an enhanced usage and further growth of the recently upgraded infrastructure for ICT research in Lithuania.”","modality":"planned","hypothesis":null,"quote":"The long-term vision for InnoITeam is to:● Become the leading provider of innovative technologies for IoT and Big Data for the improvement of the growing technological personal and industry needs in Europe;● Consolidate research and development, education and training, and networking and promotion resources activities in Information and Communications Technology (ICT); 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● Coordinate, integrate and support research excellence and innovation development in Lithuania, the Baltic Sea region, and Europe;● Support researchers, academics, industry partners and entrepreneurs in the field of ICT, particularly in IoT, to produce innovations beneficial for the society and economy of Lithuania and beyond.To achieve this long-term vision, the CoE will leverage the knowledge, experience and resources of three Lithuanian institutions – KTU, VGTU and SECR- with the support of two advanced EU partners from Sweden – LiU and TII – in four strategic research and innovation (R&D) topics: R&D Topic 1: User interfacing and interaction design approaches for Smart Environments based on IoT;R&D Topic 2: Cybersecurity aspects in the Smart Environments based on IoT;R&D Topic 3: Data analysis and visualization approaches for data intensive IoT environments;R&D Topic 4: Cognitive IoT technologies for Smart Home Environments.This project has the full support of the Lithuanian Government because it fits perfectly with several of the national priorities within the SMART Specialisation Strategy approved by the Government, and, will allow an enhanced usage and further growth of the recently upgraded infrastructure for ICT research in Lithuania.","start":348,"text_hash":"3f11192beb7a9f50e14fe2b1b0413316029cb365d224d4184c3db3306139b6a5"},{"end":347,"kind":"text","quote":"To address and promote growth in several technological sectors in Lithuania and encourage EU teaming in ICT-related research and innovation, the overall objective of the project is to create a new Centre of Excellence (CoE) in IT Science and Technology for the Internet of Things and Smart Living Systems, which will be referred to as “InnoITeam”.","start":0,"text_hash":"3f11192beb7a9f50e14fe2b1b0413316029cb365d224d4184c3db3306139b6a5"}],"sourceVersion":"eb2a1b605eebd45de7daad0d4ff171babdd9cf628827826cc3c12a5bd96c31aa","originalAssertionId":"c7fe1d2b445eddec05f440cc79035970aaf6dfcff383dc1b554eab0381b60542","methodVersion":"mesh-semantic-contract-2.4.7","model":"mlx-community/Qwen3.5-9B-4bit","modelRevision":"8b2b98c00a6b4d291155e4890773ca8f769aee53","rubricHash":"134e27d7b3c423001f4ffa02f11e04f0e3d78a5b199867c1fa4a4fa0e579f2e5","recordedAt":"2026-09-28T13:34:34.663515+00:00","reviewHistory":[],"validTime":{"kind":"unknown"},"contractVersion":"mesh-semantic-contract-2.4.7","claimBasis":{"activity_id":"act-84e8b805723ed89d09a8a74f","activity_ref":"a7","claim_unit_candidates":["a7","a8"],"end":1984,"evidence_id":"s2","ownership":"current_project","quote":"The long-term vision for InnoITeam is to:● Become the leading provider of innovative technologies for IoT and Big Data for the improvement of the growing technological personal and industry needs in Europe;● Consolidate research and development, education and training, and networking and promotion resources activities in Information and Communications Technology (ICT); 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● Coordinate, integrate and support research excellence and innovation development in Lithuania, the Baltic Sea region, and Europe;● Support researchers, academics, industry partners and entrepreneurs in the field of ICT, particularly in IoT, to produce innovations beneficial for the society and economy of Lithuania and beyond.To achieve this long-term vision, the CoE will leverage the knowledge, experience and resources of three Lithuanian institutions – KTU, VGTU and SECR- with the support of two advanced EU partners from Sweden – LiU and TII – in four strategic research and innovation (R&D) topics: R&D Topic 1: User interfacing and interaction design approaches for Smart Environments based on IoT;R&D Topic 2: Cybersecurity aspects in the Smart Environments based on IoT;R&D Topic 3: Data analysis and visualization approaches for data intensive IoT environments;R&D Topic 4: Cognitive IoT technologies for Smart Home Environments.This project has the full support of the Lithuanian Government because it fits perfectly with several of the national priorities within the SMART Specialisation Strategy approved by the Government, and, will allow an enhanced usage and further growth of the recently upgraded infrastructure for ICT research in Lithuania.","reason":"purpose: Code: support could not be attributed: passage(s) s2 describe both the project's own work and other work, and the selected activity is not the project's own. 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sciences","Psychology","Medical engineering","Political science","Mechanical engineering","Technology management","Social and economic geography","Sociology"],"description":"Specific Challenge:Despite a recent tendency for the research and innovation performances of individual countries in the EU to converge, sharp differences among Member States still remain. These disparities are due to, among other reasons, the insufficient critical mass of science and lack of centres of excellence having sufficient competence to engage countries and regions strategically in a path of innovative growth, building on newly developed capabilities. Moreover, by putting national budgets under constraint, the ongoing financial crisis is threatening to widen gaps. Exploiting the potential of Europe's talent pool by maximising and spreading the benefits of research and innovation across the Union is vital for Europe's competitiveness and its ability to address societal challenges in the future. This could help countries and regions that are lagging behind in terms of research and innovation performance to attain a competitive position in the global value chains.\nTeaming will address this challenge by supporting the creation of new centres of excellence or upgrading the existing ones in low R&I performing countries, building on partnerships between leading scientific institutions and partner institutions in low R&I performing countries, that display the willingness to engage together on this purpose.\nScope:Teaming, will involve in principle, two (2) parties:\n(1) The main applicant organisation (the coordinator) established in a \"Widening\" country (see section on specific eligibility criteria for more details) that must be either a national/regional authority or a research funding agency or a university or a research organisation. In case the coordinator organisation is not a public authority, it will need to provide a letter of intent (the Commission will provide a relevant template) to ensure the long-term nature and accountability of Teaming projects.\n(2) A university or research organisation with an international reputation in research and innovation excellence.\nPartner organisations will have to explain clearly their vision for the establishment of a new Centre of Excellence (or the upgrading of an existing one) that would be hosted in the \"Widening\" country. This will include details on the long-term science and innovation strategy of the future Centre, in particular, the detailed provisions for the good management of the project between the partners. Furthermore, proposers should include a clear analysis of how this strategy would fit broadly with the relevant Smart Specialisation Strategy of the Widening country, where relevant, or an equivalent growth strategy. In the case of an upgrade of an existing centre of excellence, additional information concerning organisation profile, activities and strategy of the centre should be provided.\nInformation for Teaming Phase 1:\nUnder Phase 1, successful applicants will receive a grant that will last for 12 months, to produce an extensive, detailed and robust Business Plan for the setting-up / upgrading of a Centre of Excellence.\nProposers will be asked to demonstrate within their (single) proposal two distinct, yet complementary aspects:\n• a long term vision, including a long term science and innovation strategy based on a SWOT analysis, for the new Centre of Excellence (or the upgrading of an existing one) that would be hosted in the Widening country.\n• a 12 month action aimed at producing a detailed and robust business plan for the setting-up/upgrading of the Centre of Excellence in line with the long term vision.\nThe Teaming proposal will need to demonstrate that the project is based on a true joint venture between the relevant partners from both parties. This long term joint venture cooperation is expected to continue also beyond the duration of the overall Teaming project, with the partners fully committed to continue supporting the new Centre in view of achieving sustainability in the long run and hopefully financial autonomy (also by successfully competing for European and international funding programmes).\nThe Commission considers that proposals requesting a contribution from the EU of EUR 0.40 million, would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting lower amounts.\nPreliminary Information for Teaming Phase 2 (under WP 2018/19):\nOnce the 12 month CSA under Teaming Phase 1 is concluded, there will be a restricted call for the concrete implementation of the Business Plan, i.e. for the establishment of the new/upgraded centre (Teaming, Phase 2).\nThis call will be addressed to the participants successful in Phase 1 above, and to applicants who have concluded a Framework Partnership Agreement in the context of the call H2020-WIDESPREAD-2014 and have not concluded a Specific Grant Agreement for Teaming Phase 2.\nThe submitted proposals under this restricted call will undergo an independent evaluation, and those selected for funding will be awarded a CSA grant (Teaming Phase 2).\nThis new grant for Teaming Phase 2 will provide substantial support for the start-up and implementation phase of the future Centre of Excellence. This will cover mainly administrative and operational costs as well as personnel costs of the future Centre of Excellence. While the action does not focus on equipment and consumables, these could be accepted if they constitute only a minor part of the total Horizon 2020 funding requested and may be deemed necessary to fulfil the action's specific scope and objective.\nIt is to be noted, that Horizon 2020 under the Teaming action will not support infrastructure costs associated with the new or upgraded centre. Such costs are expected to be supported by other types of funding, including where relevant by the European Structural and Investment Funds (ESIF) or the Instrument for Pre-accession Assistance (IPA II) funds.\nThe duration of a Teaming Phase 2 project may be between 5 to 7 years.\nFurther explanations for Teami","descriptionTruncated":true,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/WIDESPREAD-04-2017"}]}}
{"id":"101310826","acronym":"Letonite System","name":"Validation of a novel pilot scale system for phosphorus capture from effluent wastewater","offer":"The new Urban Wastewater Treatment Directive has tightened phosphorus (P) discharge limits in effluent wastewater. Wastewater treatment plants in EU territories were already struggling to meet previous limits and now must comply with a 50-65% reduction vs the previous regulation (from P removal of 80% to 87.5-90%) from August 2027, with the directive setting strict compliance goals from 2033 onwards.P-Agro Minerals is developing the Letonite Filter System developing a modular, end-of-pipe P removal and recovery solution designed for installation at the final discharge of municipal and industrial WWTPs. The system boasts a proprietary design and our novel, also proprietary Letonite media: a novel media based on natural, mineral materials optimized to capture over 90% of residual P directly in flowing wastewater. This solution achieves lower costs versus chemical coagulant treatment, and is easily retrofittable in existing WWTPs, directly targeting the needs of small to medium scale operators struggling to adapt to emerging regulators.Besides achieving P-removal compliance, our technology uniquely enables P circularity, as used Letonite can be recovered and used as soil amendment, closing the loop between wastewater and agriculture.This EIC Pre-Accelerator project aims to advance the technology from small-scale to pilot scale validation at a WWTP. The core technical objective is the development and validation of a pilot-scale unit achieving stable operations and regulatory compliant P-removal. The project also supports establishing the Letonite Filter System value chain with all key stakeholders in Latvia as well as generating initial traction in target EU markets in preparation for the next phases: industrialization and subsequent market entry. With this, P-Agro accelerates its development roadmap towards market readiness in time to generate the needed impact in the EU wastewater treatment industry as well as environmental and circularity goals.","objective":"The new Urban Wastewater Treatment Directive has tightened phosphorus (P) discharge limits in effluent wastewater. Wastewater treatment plants in EU territories were already struggling to meet previous limits and now must comply with a 50-65% reduction vs the previous regulation (from P removal of 80% to 87.5-90%) from August 2027, with the directive setting strict compliance goals from 2033 onwards.P-Agro Minerals is developing the Letonite Filter System developing a modular, end-of-pipe P removal and recovery solution designed for installation at the final discharge of municipal and industrial WWTPs. The system boasts a proprietary design and our novel, also proprietary Letonite media: a novel media based on natural, mineral materials optimized to capture over 90% of residual P directly in flowing wastewater. This solution achieves lower costs versus chemical coagulant treatment, and is easily retrofittable in existing WWTPs, directly targeting the needs of small to medium scale operators struggling to adapt to emerging regulators.Besides achieving P-removal compliance, our technology uniquely enables P circularity, as used Letonite can be recovered and used as soil amendment, closing the loop between wastewater and agriculture.This EIC Pre-Accelerator project aims to advance the technology from small-scale to pilot scale validation at a WWTP. The core technical objective is the development and validation of a pilot-scale unit achieving stable operations and regulatory compliant P-removal. The project also supports establishing the Letonite Filter System value chain with all key stakeholders in Latvia as well as generating initial traction in target EU markets in preparation for the next phases: industrialization and subsequent market entry. With this, P-Agro accelerates its development roadmap towards market readiness in time to generate the needed impact in the EU wastewater treatment industry as well as environmental and circularity goals.","sourceVersion":"eb9fd987aae7e23696e650b809411d59a1c089c2996b076f5a97436624bb8c12","originalSourceVersion":"8c1cace30347ca5e73f86419a6cb9abf168e95d2f20029a59b7cd146c3aab2b6","textHash":"0d29c117b5e246c3161d4746d429da423569de742ba565a5dec65f70ef6f53b6","sourceUrl":"https://cordis.europa.eu/project/id/101310826","country":"LV","participantCountries":["LV"],"programme":"HORIZON","status":"SIGNED","sourceUpdated":"2026-07-19 17:08:00","locations":[],"goal":6,"goalIds":[6,9,12],"rels":[{"code":"12.4","name":"By 2020, achieve the environmentally sound management of chemicals and all wastes throughout their life cycle, in accordance with agreed international frameworks, and significantly reduce their release to air, water and soil in order to minimize their adverse impacts on human health 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Such companies often struggle to attract financing because the technology and investment risks are too high.\nIn the framework of this call, deep-tech[1] is technology that is based on cutting-edge scientific advances and discoveries and is characterised by the need to stay at the technological forefront by constant interaction with new ideas and results from the lab. Deep-tech innovations are understood to be those that have the potential to deliver transformative solutions, rooted in cutting-edge science, technology, and engineering, including innovation that combines advances in the physical, biological and digital spheres. 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This includes specific milestones together with concrete and verifiable KPIs to assess progress towards the market.\nThe support will be in awarded by grants max at 70% funding of the eligible costs. 30% co-funding to be covered by the beneficiary through its own resources.\nAn amount between EUR 300.000 and max EUR 500.000 in the form of a lump sum for a period of up to 2 years is considered appropriate.\nSeal of Excellence will be awarded to all proposals that meet the evaluation thresholds but are not funded due to lack of available budget.\nThe requested grant is expected to be used for:\n• addressing the investor and market readiness towards commercialisation and deployment (market research, value proposition, business case and business model, prospects for growth, intellectual property protection, competitor analysis etc.) and if relevant, aspects of regulation, certification and standardisation, aimed at getting both the technology and the business idea investment ready and/or;\n• the maturation and validation of novel technologies beyond proof of concept to viable demonstrators of the technology in the intended field of application (i.e., from minimum TRL 4 up to TRL 6).\nAt the end of the EIC Pre-accelerator project, it needs to:\n• demonstrate that the technology component of their innovation has been tested and validated in a laboratory and other relevant environment (e.g. at least completed all aspects of TRL 5);\n• be ready to apply for EIC Accelerator and/or to seek other investors or sources of funding, to enter licensing or collaboration agreements with third parties, or other routes to market deployment.\nSuccessful applicants and those awarded the Seal of Excellence will be granted free access to the EIC Business Acceleration Services[4], such as coaching and specific events tailored to their needs (e.g. for improving investor and market readiness).\nThis will be complemented by access to the EIC Accelerator Fast Track[5] for submissions to the Accelerator programme following a project review in the second half of the project.\n[1]  Deep-tech ventures have the following characteristics: positioning at the knowledge frontier with long and uncertain R&I cycles; relates to tangible products and industrialisation processes; linked to the ecosystem and especially higher education institutions, problem orientated, or mission driven, focused on the creation of an option space and a dynamic de-risking cycle.\n[2]  Ratio of a firm’s R&D investment to its revenue.\n[3]  Completed TRL 5 (Technology validated in relevant environment – industrially relevant environment in the case of key enabling technologies) or TRL6 (Technology demonstrated in relevant environment -industrially relevant environment in the case of key enabling technologies). For more information, see EIC Work Programme 2025.\n[4]  See EIC Work Programme 2025. More information is available also here: https://eic.ec.europa.eu/eic-funding-opportunities/business-acceleration-services_en.\n[5]  See Annex 3 Fast Track scheme to apply for the EIC Accelerator, EIC Work Programme 2025.","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-WIDERA-2025-02-ACCESS-01"}]}}
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Thanks to the unprecedented technological development, it is now possible to label single cells within the eye lens, and to follow the path of its daughter cells. The Bassnett lab at Washington Univ School of Medicine is the leader in this labelling technique and has a very ambitious program to answer questions above. Two years ago we joined Prof. Steven Bassnett in this fascinating endeavor. We bring more than 20 years of research experience in probability theory and mathematical analysis, leadership on several NSF grants, as well as more than 10 years of leading the Division of Prob. & Stats, Dept of Mathematics, Univ of Zagreb. We propose to develop mathematical models of various stages in the growth of the lens. Initial period of our collaboration is completed and we are now at the level where daily contact is needed. Our model is Markov in nature, and would involve branching processes with immigration and emigration. 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Remanufacturing aims to retain the usefulness of both products and components and is an essential step in achieving full industrial circularity without implying deterioration of the product.\nThis calls for both remanufacturing technologies at the factory level and their integration into circular value chains, including the streamlining data to support remanufacturing. Remanufacturing should not be focused only on the reuse of raw materials but should be aimed at reusing and upscaling components, valorising them and retaining or upgrading their functionality. Components, products and/or functions can be updated with new technology and improved beyond their initial functionality. Ultimately, remanufacturing is indirectly expected to reduce the level of resource consumption and hence also the level of CO2-intensity of components.\nProposals should address technologies within specific industrial sectors or across industrial sectors:\n• Develop cutting-edge remanufacturing approaches (design, technologies, business cases) and their integration into value chains;\n• Demonstrate remanufacturing processes that retain components functionality in at least three user cases;\n• The introduction of traceability aspects, quality control and a regulatory validation need to be considered;\n• Repurposing of components into a variety of industrial sectors. Introduce flexible production concepts, advanced machinery, smart mechatronics, interactive and collaborative machines, robots and systems enabling efficient factory operation and reconfiguration;\n• Consider operational and economic viability while also the environmental impact of the proposed approach.\nA human-centric approach to remanufacturing should be integrated, with appropriate contributions from Social Sciences and Humanities (SSH); as part of this, a strategy for skills development should be included, associating social partners where relevant. This may include augmenting technologies and skills to strengthen the capabilities of the European workforce. 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{"id":"101064696","acronym":"I-SEE","name":"Cell Rejuvenation Therapy for Age-related Macular Degeneration","offer":"Age-related macular degeneration (AMD) is a leading cause for blindness, resulting in loss of vision at the center of the visual field - the macula, due to damage to the retina. The disease, usually affecting older adults (>55), was diagnosed in 2020 in 196 million people worldwide, with an estimated economic toll of $343 billion including $255 billion in direct healthcare costs. In AMD, photoreceptors and retinal pigmented epithelium (RPE) cells which underlie the photoreceptors undergo degeneration. The standard care is injections of anti-VEGF medicines such as ranibizumab (Lucentis), aflibercept (Eylea) and brolucizumab (Beovu) to the eye every 1-3 months. These delay disease progress but cannot restore lost vision, and have side effects such as bleeding in the eye. During an ERC Starting project, the PI has discovered a new method that would allow to not only delay the disease but to also improve RPE cells function as a treatment for AMD. The proposed approach to rescue RPE cells is rejuvenation by a technique called partial reprogramming. Our results suggest that the proposed technique is safe and efficient in rejuvenating mouse and human fibroblasts, and in improving their function. In the current application, through in vivo studies, we will prepare for implementing our novel approach in our envisioned product I-SEE. In I-SEE, we will aim to use our discovery of a unique combination of factors, that successfully reprogram cells, to drive aging RPE cells into rejuvenation and improved function. We will calibrate the expression of the reprogramming factors in RPE cells, and test rejuvenation and improved function in AMD mouse models. IPR and partnering with clinician and industry will be developed concomitantly. Our final product, I-SEE, is developed based on a PCT patent Application No. 63/210,030, as a cocktail of molecules of mRNA directly applied to the eye, to offer the first AMD treatment that could restore vision.","objective":"Age-related macular degeneration (AMD) is a leading cause for blindness, resulting in loss of vision at the center of the visual field - the macula, due to damage to the retina. The disease, usually affecting older adults (>55), was diagnosed in 2020 in 196 million people worldwide, with an estimated economic toll of $343 billion including $255 billion in direct healthcare costs. In AMD, photoreceptors and retinal pigmented epithelium (RPE) cells which underlie the photoreceptors undergo degeneration. The standard care is injections of anti-VEGF medicines such as ranibizumab (Lucentis), aflibercept (Eylea) and brolucizumab (Beovu) to the eye every 1-3 months. 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{"id":"101068441","acronym":"EC-MAXene","name":"Green electrochemical synthesis and characterization of MXenes for sustainable energy","offer":"To minimize the consequences of climate change, stopping greenhouse gas emissions and thus decarbonization of the energy supply chain is crucial. A highly promising solution is the utilization of fuel cells, which require hydrogen for energy generation. The supply of hydrogen by green technologies like water splitting is not economically feasible yet. To resolve this issue, cheap and efficient catalysts to drive this reaction are required. In the recent years, 2D materials moved in the focus of research as some of them show excellent catalytic activity to support the electrochemical splitting of water to obtain hydrogen.Among the vast field of 2D materials, MXenes are potential earth-abundant candidates with high stability and a broad range of potential applications, including the catalysis of water splitting. To date, 30 different MXenes have been synthesized, while more than 100 of them are predicted. However, established protocols use hazardous chemicals for the synthesis. Among the different methods, electrochemical etching of MAX phases to MXenes has the highest potential for an environmental approach. Thus, the main effort of this project is to develop electrochemistry-based synthesis routes for MXenes using environmentally friendly chemicals. The developed techniques will be evaluated in terms of yield and the structural and electrochemical characteristics of MXenes will be correlated.The etching process will be further optimized using scanning electrochemical microscopy. The technique enables the analysis of the localized electrochemical activity and the electrocatalytic activity towards the hydrogen evolution reaction. This will provide a deeper knowledge about the etching process in two regards: The minimum time required to achieve full conversion of MAX phase to MXene on an electrode surface can be determined, and local differences in catalytic activity can be spotted and correlated with structural and chemical deviations.","objective":"To minimize the consequences of climate change, stopping greenhouse gas emissions and thus decarbonization of the energy supply chain is crucial. A highly promising solution is the utilization of fuel cells, which require hydrogen for energy generation. The supply of hydrogen by green technologies like water splitting is not economically feasible yet. To resolve this issue, cheap and efficient catalysts to drive this reaction are required. In the recent years, 2D materials moved in the focus of research as some of them show excellent catalytic activity to support the electrochemical splitting of water to obtain hydrogen.Among the vast field of 2D materials, MXenes are potential earth-abundant candidates with high stability and a broad range of potential applications, including the catalysis of water splitting. To date, 30 different MXenes have been synthesized, while more than 100 of them are predicted. However, established protocols use hazardous chemicals for the synthesis. Among the different methods, electrochemical etching of MAX phases to MXenes has the highest potential for an environmental approach. Thus, the main effort of this project is to develop electrochemistry-based synthesis routes for MXenes using environmentally friendly chemicals. 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In all its forms, cultural heritage, values, institutions and language are crucial for the collective memories and sociability of groups but also for the personal development of citizens, enabling them to find their place in society. They also serve as a source of inspiration for the development of people's personalities and talents. Extending to the very heart of Europe and constituting a basis for EU construction, they play a key role in providing a sense of European belonging and EU citizenship as distinct from, but combined with, national citizenship. Cultural heritage and values are at the heart of our capability of overcoming the current EU crisis which could well provide the stimulus for revising EU policies so as to provide a solid basis for the emergence of a truly European cultural heritage and for passing it to future generations. The challenge is to explore and show how critical reflection on the historical, cultural and normative roots of Europe´s cultural and democratic practices and institutions contribute to an evolving European identity today.\nScope: The multidisciplinary and comparative research will focus on the emergence of a European cultural heritage in a historical perspective and the best way to transmit it. The content and methodology of education and curricula should be taken into account, as well as the role of new technologies and media. It will address how the local, regional, national and European aspects of cultural heritage are interlinked, how they are understood or not by citizens and encouraged or not by various stakeholders and promoters of cultural heritage. It will also analyse how this interplay of cultural heritage at different levels impacts on Europeanisation and the citizens' perceptions on Europe. The research will focus on the place of critical reflection in sustaining this as a cultural resource. This research should include both tangible and intangible cultural heritage as well as less established or popular examples of cultural heritage in the area of the living arts and consider contemporary trends in arts and culture in the shaping of tomorrow's European cultural heritage in order to enrich the study differentiating between commercial and non-commercial aspects. The research will also focus on the multilingual nature of the European heritage, seeking to gain a deeper understanding of the axiological, linguistic, social and cultural aspects of multilingualism and how they ensure the transmission of cultural heritage across generations and borders.\nThe links between the valorisation of this combined cultural heritage and various forms of formal and non-formal education and training, as well as the development of social, axiological, linguistic, cultural and political memories or imaginaries, should be studied in order to assess potential trends towards various forms of European cultural heritage and its links with Europeanisation. This should also include the assessment of the touristic potential of the EU level cultural heritage.\nThe Commission considers that proposals requesting a contribution from the EU of between EUR 1.5 and 2.5 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.\nExpected impact: Research will support the EU cultural policies linked to fostering the emergence, transmission and use of cultural heritage at local regional, national and, in particular, European level.\nIt will provide the different stakeholders at all relevant levels in various sectors of cultural heritage with an ambitious  approach to sharing its development and preservation at the different levels, suggesting innovative synergies between various levels of responsibility. These activities are expected to offer practical advice, best practices and a set of proposals regarding European cultural and educational institutions that could promote European cultural heritage and its use in Europe and internationally in full cooperation with relevant authorities and experts and the due participation of EU citizens at relevant levels.\nType of action: Research and innovation actions\nCross-cutting Priorities:Socio-economic science and humanities","descriptionTruncated":false,"portalUrl":"https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/REFLECTIVE-2-2015"}]}}
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Individual SMEs are at a disadvantage to recruit specialised knowledge as they often lack Europe-wide networking connections and do not tend to have established brands as large enterprises. Enterprise-led mobility programmes, supporting enterprises in recruiting expertise, show a high level of satisfaction and return on investment. This methodology is not currently used at European level and this enterprise-led approach is to be further developed and tested, using the first experiences of this pilot action financed by the work programme 2016-2017. This action complements Marie Skłodowska Curie actions (MSCA) which focus on developing research careers, by providing additional work opportunities for experienced researchers in innovating SMEs.\nThis action is a continuation of the pilot action, which is part of the Innovation in SMEs work programme 2016-2017. The first \"innovation associates\" supported by the 2016-2017 pilot started working in SMEs as of September 2017 onwards. The detailed provisions and the conditions of the action in 2019-2020 are therefore subject to revision based on the conclusions from the first pilot, including also the findings of the accompanying study to INNOSUP-02-2016 that is conducted in parallel to INNOSUP-02-2016.\nScope:This SME-led pilot is an innovation capacity building action to provide a grant at European level to visionary[1] SMEs that can demonstrate that the skills required for a particular innovation idea are not within reach for them at national level (for example because the required skills are not available or not affordable for SMEs). SMEs are supported to employ a highly skilled experienced researcher (referred to as an 'innovation associate') for a continuous period of one year. The innovation associate's task will be to explore, during the course of his/her contract, the potential of their innovative idea and turn it into an innovation project.\nThe evaluation of proposals will focus on the demonstrated benefits of recruiting transnationally i.e. the impact for the SME to get access to skills not available on the national labour market; the excellence and impact of the innovative idea, as well as the coherence and effectiveness of the recruitment plan, which should offer the same opportunities for male/female candidates.\nSMEs that will receive a grant will be obliged to advertise their vacancy on EURAXESS, unless a contract with an innovation associate has already been signed in line with the provisions above. They are also encouraged to publish the vacancy notice on any other relevant platform or media, with a clear indication that the grant was awarded.\nSMEs that are awarded a grant are obliged to employ an \"innovation associate\" for a continuous period of one year[2]. The innovation associate's tasks shall be to identify the potential of the company's innovation idea with the objective and turn it into an innovation project and - hopefully - a continuation of the employment of the innovation associate. During the period covered by the grant, the Innovation Associate must work exclusively on the project described in the grant agreement.\nDuring these 12 months of employment, every associate is requested to participate in a core training programme on industrial innovation and business management[3]. Also during that period, SMEs get financial support to implement a training and development plan specifically for the associate, tailored to the needs of the associate and the enterprise to make the associate fully operational in the company. Proposals shall outline how the proposed tailored training contributes to this end and why it is necessary within the context of the innovation idea and the tasks of the innovation associate.\nIn line with the orientation of the action and with the aim to accelerate the integration of the associate in the company's staff, the following costs shall be eligible for reimbursement under the grant:\n• Personnel costs of the associate.\n• Relocation costs of the associate, which may include removal cost, travel cost of the associate and his/her immediate family (if applicable) to the new place of employment, visa cost (if applicable), translation cost of certificates (if applicable), a temporary transition allowance to cover extra costs upon arrival in the place of employment, cost for the relocation in the country of origin after the project, as well as other clearly justified expenditure directly related to relocation.\n• Travel and subsistence costs of the associate to the core training programme and travel and subsistence for tailored training (as described in the personal development plan). 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It will further strengthen the innovation dimension of the widening component and increase the overall competitiveness of these countries.\nThe specific outcome expected of this action is increased business, investor, and technology readiness of high potential deep-tech startups in widening countries to a level where they will:\n• be successful in applying and attracting the EIC Accelerator funding and/or;\n• manage to secure other private investment and/or;\n• attract successfully national or regional funding as alternative funding sources (e.g. through Seal of Excellence programmes).\nScope:This action focuses on early-stage deep-tech startups which 1) have high-impact innovation technology, product, service, or business model that could create new markets or disrupt existing ones, and 2) have the ambition and commitments to scale up.\nThe successful applicants need to work on deep tech innovation. Such companies often struggle to attract financing because the technology and investment risks are too high.\nIn the framework of this call, deep-tech[1] is technology that is based on cutting-edge scientific advances and discoveries and is characterised by the need to stay at the technological forefront by constant interaction with new ideas and results from the lab. Deep-tech innovations are understood to be those that have the potential to deliver transformative solutions, rooted in cutting-edge science, technology, and engineering, including innovation that combines advances in the physical, biological and digital spheres. Deep-tech is distinct from ‘high-tech’ which tends to refer only to R&D intensity[2].\nThis EIC Pre-accelerator - Widening call is designed to enable promising deep-tech startups to develop further their innovations (from TRL 4 to TRL 5/6)[3], attract the investment amounts needed for scale up in a shorter timeframe and successfully apply and attract funding from EIC Accelerator or other sources.\nThe applicants are expected to demonstrate in their application that they:\n• have developed technology validated in the lab (at least TRL 4);\n• possess the necessary Intellectual Property Rights to ensure freedom to operate and adequate protection of the idea;\n• have a clear vision on the intended pathway and route to market. This includes specific milestones together with concrete and verifiable KPIs to assess progress towards the market.\nThe support will be in awarded by grants max at 70% funding of the eligible costs. 30% co-funding to be covered by the beneficiary through its own resources.\nAn amount between EUR 300.000 and max EUR 500.000 in the form of a lump sum for a period of up to 2 years is considered appropriate.\nSeal of Excellence will be awarded to all proposals that meet the evaluation thresholds but are not funded due to lack of available budget.\nThe requested grant is expected to be used for:\n• addressing the investor and market readiness towards commercialisation and deployment (market research, value proposition, business case and business model, prospects for growth, intellectual property protection, competitor analysis etc.) and if relevant, aspects of regulation, certification and standardisation, aimed at getting both the technology and the business idea investment ready and/or;\n• the maturation and validation of novel technologies beyond proof of concept to viable demonstrators of the technology in the intended field of application (i.e., from minimum TRL 4 up to TRL 6).\nAt the end of the EIC Pre-accelerator project, it needs to:\n• demonstrate that the technology component of their innovation has been tested and validated in a laboratory and other relevant environment (e.g. at least completed all aspects of TRL 5);\n• be ready to apply for EIC Accelerator and/or to seek other investors or sources of funding, to enter licensing or collaboration agreements with third parties, or other routes to market deployment.\nSuccessful applicants and those awarded the Seal of Excellence will be granted free access to the EIC Business Acceleration Services[4], such as coaching and specific events tailored to their needs (e.g. for improving investor and market readiness).\nThis will be complemented by access to the EIC Accelerator Fast Track[5] for submissions to the Accelerator programme following a project review in the second half of the project.\n[1]  Deep-tech ventures have the following characteristics: positioning at the knowledge frontier with long and uncertain R&I cycles; relates to tangible products and industrialisation processes; linked to the ecosystem and especially higher education institutions, problem orientated, or mission driven, focused on the creation of an option space and a dynamic de-risking cycle.\n[2]  Ratio of a firm’s R&D investment to its revenue.\n[3]  Completed TRL 5 (Technology validated in relevant environment – industrially relevant environment in the case of key enabling technologies) or TRL6 (Technology demonstrated in relevant environment -industrially relevant environment in the case of key enabling technologies). 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Disease-prediction models that built on the basis of these novel understanding and biomarkers, significantly overpower the best currently-available prediction models. Importantly, these pioneering models can identify the people at risk well before the appearance of any clinical symptoms. Strong preliminary evidence signified the potential to develop the first clinical test to identify the risk to develop T2DM and associated diseases among non-pre-diabetic individuals at the required prediction power, and in time to deliver effective disease-preventing treatments. Validation of these results and demonstration of the effectiveness of the new clinical-level test will allows the directions of the effective (though expensive) preventing treatments to the people at risk, thus dramatically improve the way we are dealing with this harmful disease.","objective":"Type 2 Diabetes Mellitus (T2DM) is a heterogeneous disease, associated with mortality and severe morbidity, and affecting hundreds of millions of people around the globe. Despite some misconception accepted in the public, current models to predict the onset of T2DM have insufficient power, and are generally limited to individuals that already progressed into pre-diabetes states, at which the assignment of disease-preventing treatments is largely ineffective. Clinical-level prediction power (AUC>0.9) among non-diabetic individuals would enable effective pre-emptive strategies, but the way to produce such predictions remined unknown. Based on a new understanding of enhancer-silencer regulatory networks, I have developed a new class of supreme epigenetic biomarkers. Disease-prediction models that built on the basis of these novel understanding and biomarkers, significantly overpower the best currently-available prediction models. Importantly, these pioneering models can identify the people at risk well before the appearance of any clinical symptoms. Strong preliminary evidence signified the potential to develop the first clinical test to identify the risk to develop T2DM and associated diseases among non-pre-diabetic individuals at the required prediction power, and in time to deliver effective disease-preventing treatments. 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{"id":"101231399","acronym":"AutoKnow","name":"Authoritarian Threats to Scientific Knowledge","offer":"The growth of scientific knowledge is a towering achievement of humankind, but its societal causes remain underexplored. What makes some societies more fertile for science? AutoKnow will answer this by investigating how authoritarian rule affects scientific knowledge production. Authoritarian regimes are investing heavily in science and democratic backsliding threatens several democracies. How is science affected by authoritarian rule? AutoKnow will address this, elaborating a new theory of 'science and authoritarian rule' explaining how scientific knowledge production is affected by i) authoritarian regimes vs. democracies, ii) authoritarian regime features (e.g., ideology, repression, institutions), and iii) authoritarian politics in backsliding democracies. To test the theory, AutoKnow will compile global data on attacks on science, published scientific output, and (surveys of) social norms relating to science (among scientists), linked to data on authoritarian rule across countries and levels of analysis. The project will study when and why authoritarian rulers launch attacks on scientists, and if authoritarian rule influences scientific norms (among scientists) using survey-data. Crucially, AutoKnow considers the effects of authoritarian rule on the contents of scientific publications, focusing on scientific progress and political influence. AutoKnow will use computational language-model analysis of millions of published scientific abstracts to capture performance dimensions, e.g. scientific disruptiveness and idea novelty, and in the social sciences and humanities, political bias and censorship. These insights will be integrated with state-of-the-art data on authoritarian rule, authoritarian regime features and politics at various levels (e.g., countries and academic institutions). AutoKnow will reveal how authoritarian rule impacts science, helping stakeholders protect scientific progress in the face of authoritarian threats.","objective":"The growth of scientific knowledge is a towering achievement of humankind, but its societal causes remain underexplored. What makes some societies more fertile for science? AutoKnow will answer this by investigating how authoritarian rule affects scientific knowledge production. Authoritarian regimes are investing heavily in science and democratic backsliding threatens several democracies. How is science affected by authoritarian rule? AutoKnow will address this, elaborating a new theory of 'science and authoritarian rule' explaining how scientific knowledge production is affected by i) authoritarian regimes vs. democracies, ii) authoritarian regime features (e.g., ideology, repression, institutions), and iii) authoritarian politics in backsliding democracies. To test the theory, AutoKnow will compile global data on attacks on science, published scientific output, and (surveys of) social norms relating to science (among scientists), linked to data on authoritarian rule across countries and levels of analysis. The project will study when and why authoritarian rulers launch attacks on scientists, and if authoritarian rule influences scientific norms (among scientists) using survey-data. Crucially, AutoKnow considers the effects of authoritarian rule on the contents of scientific publications, focusing on scientific progress and political influence. 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The European Commission adopted on 6th of October a comprehensive Economic and Investment Plan for the Western Balkans (COM(2020) 641, 6/10/2020) , which aims to spur the long-term economic recovery of the region, support a green and digital transition, foster regional integration and convergence with the European Union.\nTwinning aims to enhance networking activities between the research institutions of the Western Balkan Countries and top-class leading counterparts at EU level by linking it with at least two research institutions from two different Member States or Associated Countries. Therefore, building on the huge potential of networking for excellence through knowledge transfer and exchange of best practice between research institutions and partners. 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