Centro Común de Investigación
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Multiple Primary Tumour validation ontology
OWL ontology for validating the international rules for multiple-primary malignant tumours. The first version includes all the necessary files for importing, later versions require the...
OWL
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EURL ECVAM Review of non-animal models in biomedical research - Cardiovascular diseases
Among non‐communicable diseases, CVDs are the major cause of death in Europe and worldwide, causing 32% of all deaths in the world. Experimental models are essential to understand disease...
Excel XLSX
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Nanoparticle-based vaccines in clinical trial/use for COVID-19 and licensed for other pathogens
While several COVID-19 Nanoparticle-based vaccines have been developed during the past year, prior to this pandemic only a small number of NVs have been approved for human use (hepatitis,...
Excel XLSX
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Ruthenium-106 event (total gamma dose rates)
Between the end of September and early October 2017, several European networks involved in the monitoring of atmospheric radioactive contamination recorded 106Ru presence. Some regions of...
CSV (128 presentación) (108 Descargas)
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A Systematic Review of Published Physiologically-based Kinetic Models and an Assessment of their Chemical Space Coverage
Across multiple sectors, including food, cosmetics and pharmaceutical industries, there is a need to predict the potential effects of xenobiotics. These effects are determined by the...
Excel XLSX
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JRC QSAR Model Database
The JRC QSAR Model Database is a historical archive providing information on the validity of Quantitative Structure-Activity Relationship (QSAR) models that were submitted to JRC's EU...
HTML ZIP (68 presentación) (46 Descargas)
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Three Rs Education and Training Courses and Resources
The purpose of the collection of these data undertaken between June and September in 2018 was to provide a snapshot overview of education and training courses and resources on the theory...
Excel XLS (79 presentación) (63 Descargas)
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EURL ECVAM Review of non-animal models in biomedical research - Immunogenicity Testing of Advanced Therapy Medicinal Products (ATMP)
This highly curated knowledge base contains detailed descriptions of 88 non-animal models being used for immunogenicity in ATMP, mostly employed to test cell therapy products. T cells...
Excel XLSX
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EURL ECVAM in vitro hepatocyte clearance and blood plasma protein binding dataset for 77 chemicals
The European Commission’s Joint Research Centre (JRC) runs the EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) which promotes regulatory acceptance of non-animal...
ZIP (8 presentación) (6 Descargas)
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EURL ECVAM library of reference chemicals
The EURL ECVAM library of reference chemicals is a catalogue of chemical lists that can be used to standardise, qualify, characterise or compare in vitro, in chimico and in silico methods...
Excel XLSX HTML
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Resources for Organ-on-Chip validation and qualification - EUROoCS RAB
To promote the use of Organ-on-Chip (OoC) devices for regulatory applications, EURL ECVAM created a catalogue of resources for developers and end-users to support validation and...
Excel XLSX
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Three Rs Education and Training Learning Scenarios
This dataset is a publicly accessible collection of learning scenarios which have been created by education professionals for use by educators who wish to teach topics under the umbrella...
HTML ZIP (5 Descargas)
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Survey Results on the validity of complex in vitro models
The survey constitued of 14 multiple answer questions, aimed to understand the stakholders' opinion on the current credibility and validity of complex in vitro models such as 3D...
Excel XLS
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OFFICAIR - Indoor air pollution in modern office buildings
OFFICAIR is a European collaborative project, which has received funding from the European Union, in the 7th Framework Program. The overall objective of the OFFICAIR project is twofold:...
CSV
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EURL ECVAM indicators to assess the impact of EU-funded research into Alzheimer's Disease, Breast Cancer and Prostate Cancer
Biomedical research is extremely resource intensive. Therefore, monitoring its outputs and impacts can be considered a priority to gain an understanding of the most productive research...
Excel XLSX
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EURL ECVAM Review of non-animal models in biomedical research - Autoimmune diseases
This highly curated knowledge base contains detailed descriptions of 183 non-animal models and recorded a sharp increase in the number of articles employing them between 2016 and 2018...
Excel XLSX
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EURL ECVAM In Vivo Repeated Dose Toxicity Database
Repeated dose toxicity studies in animals form the basis of chemical safety evaluations. Many parameters can be measured and analysed to assess the potential of the test chemical to cause...
ZIP
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SINPHONIE - Schools Indoor Pollution and Health Observatory Network in Europe database on chemical and biological pollutants
The SINPHONIE project established a scientific/technical network to act at the EU level with the long-term perspective of improving air quality in schools and kindergartens, thereby...
CSV (1 Descargas)
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ENCR core validation ontology
The ENCR (European Network of Cancer Registries) core validation ontology describes the relations and inter-variable dependencies between the ENCR core data variables. The first version,...
OWL (225 presentación) (146 Descargas)
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Stage validation ontology
A set of OWL ontologies for validating cancer stage according to a variety of stage classifications. Each stage ontology is an OWL file that may require the importing of other OWL files....
OWL